Department of Veterinary Surgery, College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
J Vet Sci. 2024 Jul;25(4):e53. doi: 10.4142/jvs.24146.
This case report presents the successful surgical removal of a pheochromocytoma in a dog using indocyanine green (ICG) fluorescence imaging.
A 10-year-old, 6.87 kg, spayed female poodle was referred for an abdominal mass and eight episodes of vomiting. Computed tomography revealed masses in the spleen and left adrenal gland. Based on the plasma normetanephrine levels, the patient was diagnosed with pheochromocytoma. Subsequently, a total splenectomy and left adrenalectomy were performed. A dose of 5 mg/kg ICG was administered intravenously 24 h prior to surgery. Using ICG allowed visualization of tumor margins, aiding in complete resection and minimizing anesthesia-related risks.
No evidence of recurrence or metastasis has been observed for 12 months. To our knowledge, this is the first report of the surgical removal of a pheochromocytoma using intraoperative ICG imaging in veterinary medicine. This case highlights the efficacy of ICG fluorescence imaging as a valuable tool for the surgical management of adrenal tumors in veterinary medicine.
本病例报告介绍了一例使用吲哚菁绿（ICG）荧光成像成功切除犬嗜铬细胞瘤的病例。
一只 10 岁、6.87 公斤的已绝育雌性贵宾犬因腹部肿块和 8 次呕吐而被转诊。计算机断层扫描显示脾脏和左肾上腺有肿块。根据血浆去甲变肾上腺素水平，该犬被诊断为嗜铬细胞瘤。随后进行了全脾切除术和左肾上腺切除术。手术前 24 小时静脉注射 5mg/kg 的 ICG。使用 ICG 可以观察到肿瘤边缘，有助于完全切除肿瘤，并最大限度地降低麻醉相关风险。
12 个月来未观察到复发或转移的证据。据我们所知，这是兽医界首例使用术中 ICG 成像切除嗜铬细胞瘤的报告。本病例强调了 ICG 荧光成像作为兽医肾上腺肿瘤手术管理的一种有价值的工具的功效。
