Institute of Applied Medical Engineering, Helmholtz Institute, Aachen, Germany.
Artif Organs. 2013 Oct;37(10):866-74. doi: 10.1111/aor.12081. Epub 2013 May 2.
The rapid evolution of rotary blood pump (RBP) technology in the last few decades was shaped by devices with increased durability, frequently employing magnetic or hydrodynamic suspension techniques. However, the potential for low flow in small gaps between the rotor and pump casing is still a problem for hemocompatibility. In this study, a spiral groove hydrodynamic bearing (SGB) is applied with two distinct objectives: first, as a mechanism to enhance the washout in the secondary flow path of a centrifugal RBP, lowering the exposure to high shear stresses and avoiding thrombus formation; and second, as a way to allow smaller gaps without compromising the washout, enhancing the overall pump efficiency. Computational fluid dynamics was applied and verified via bench-top experiments. An optimization of selected geometric parameters (groove angle, width and depth) focusing on the washout in the gap rather than generating suspension force was conducted. An optimized SGB geometry reduced the residence time of the cells in the gap from 31 to 27 ms, an improvement of 14% compared with the baseline geometry of 200 μm without grooves. When optimizing for pump performance, a 15% smaller gap yielded a slightly better rate of fluid exchange compared with the baseline, followed by a 22% reduction in the volumetric loss from the primary pathway. Finally, an improved washout can be achieved in a pulsatile environment due to the SGB ability to pump inwardly, even in the absence of a pressure head.
在过去几十年中,旋转血泵 (RBP) 技术的快速发展受到了耐久性更高的设备的影响,这些设备经常采用磁悬浮或液力悬浮技术。然而,转子和泵壳之间的小间隙中潜在的低流量仍然是血液相容性的一个问题。在这项研究中,采用了螺旋槽液力轴承 (SGB),具有两个不同的目的:首先,作为增强离心 RBP 中二次流道冲洗的机制,降低暴露于高剪切应力的风险并避免血栓形成;其次,作为允许更小间隙而不影响冲洗的方法,提高整体泵效率。应用了计算流体动力学,并通过台架实验进行了验证。对选定的几何参数(槽角、宽度和深度)进行了优化,重点是在间隙中进行冲洗,而不是产生悬浮力。与没有槽的 200μm 基线几何形状相比,优化后的 SGB 几何形状将细胞在间隙中的停留时间从 31 毫秒缩短到 27 毫秒,提高了 14%。在优化泵性能时,与基线相比,较小的 15%间隙略微提高了流体交换率,随后主要通道的体积损失减少了 22%。最后,由于 SGB 具有向内泵送的能力,即使没有压力头,也可以在脉动环境中实现更好的冲洗。