Department of Psychobiology, University of Salamanca, Neuroscience Institute of Castilla-León, Salamanca, Spain.
Eur Neurol. 2013;69(6):360-5. doi: 10.1159/000347223. Epub 2013 Apr 25.
Lexical priming was examined in patients with Alzheimer's disease and in aphasic patients. Control participants were divided into young and elderly [cf. Arroyo-Anlló et al.: Eur J Cogn Psychol 2004;16:535-553]. For lexical priming, a word-stem completion task was used. Normal elderly participants had lexical priming scores that were significantly lower than those of young individuals. Analysis of covariance with age and educational level as covariates showed that the control participants, aphasic and Alzheimer patients did not differ significantly on the lexical priming task. Our results suggest that performance in the lexical priming task diminishes with physiological aging, but is not significantly affected by mild or moderate Alzheimer's disease or by fluent or non-fluent aphasia.
词汇启动在阿尔茨海默病患者和失语症患者中进行了研究。对照组参与者分为年轻组和老年组[cf. Arroyo-Anlló 等人:Eur J Cogn Psychol 2004;16:535-553]。对于词汇启动,使用了单词词干完成任务。正常的老年参与者的词汇启动得分明显低于年轻个体。协方差分析(以年龄和教育水平为协变量)显示,在词汇启动任务中,对照组、失语症患者和阿尔茨海默病患者之间没有显著差异。我们的研究结果表明,词汇启动任务的表现随着生理衰老而下降,但不会受到轻度或中度阿尔茨海默病或流畅性或非流畅性失语症的显著影响。