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重症监护病房收治与晚期慢性疾病患者的生存状况。

Admission to the intensive care unit and well-being in patients with advanced chronic illness.

机构信息

Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.

出版信息

Am J Crit Care. 2013 May;22(3):223-31. doi: 10.4037/ajcc2013346.

Abstract

PURPOSE

To describe the association of intensive care with trajectories of functional, emotional, social, and physical well-being in patients with 3 common advanced illnesses.

METHODS

Cross-sectional cohort study of 42 patients admitted to the intensive care unit selected from 210 patients with stage IV breast, prostate, or colon cancer or stage IIIb or IV lung cancer; New York Heart Association class III or IV congestive heart failure; and chronic obstructive pulmonary disease with hypercapnea (Pco2 > 46 mm Hg). Scores on subscales of the Functional Assessment of Chronic Illness Therapy-General survey were measured monthly for 6 months before and after admission to the intensive care unit and were analyzed by using the unit admission date as a point of discontinuous change to illustrate trajectories before and after the admission.

RESULTS

Overall, trajectories of well-being declined sharply after admission to the intensive care unit. Declines in physical, functional, and emotional well-being were statistically significant. During the 6 months after admission, physical, functional, and emotional well-being scores trended back up to baseline while social well-being scores continued to decline.

CONCLUSIONS

Well-being trajectories declined sharply after admission to the intensive care unit, with recovery in the subsequent 6 months, and may be characterized by common patterns. These results help to better describe intensive care as a marker for advancing illness in patients with advanced chronic illness.

摘要

目的

描述在患有三种常见晚期疾病的患者中,重症监护与功能、情感、社会和身体福祉轨迹之间的关联。

方法

这是一项横断面队列研究,共纳入了 42 名患者,这些患者是从 210 名患有 IV 期乳腺癌、前列腺癌或结肠癌或 IIIb 期或 IV 期肺癌、纽约心脏协会(NYHA)III 或 IV 级充血性心力衰竭以及伴有高碳酸血症(Pco2>46mmHg)的慢性阻塞性肺疾病患者中选出的,他们被收入重症监护病房。在入住重症监护病房之前和之后的 6 个月内,每月测量慢性病治疗功能评估总调查的子量表评分,并通过使用入住重症监护病房的日期作为不连续变化的点来分析,以说明入住前后的轨迹。

结果

总体而言,入住重症监护病房后,患者的幸福感轨迹急剧下降。身体、功能和情感健康的下降具有统计学意义。在入住后的 6 个月内,身体、功能和情感健康评分呈上升趋势,逐渐恢复到基线水平,而社会健康评分则持续下降。

结论

入住重症监护病房后,患者的幸福感轨迹急剧下降,随后的 6 个月内逐渐恢复,可能具有共同的模式。这些结果有助于更好地描述重症监护作为晚期慢性疾病患者疾病进展的标志物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/250f/3772733/80a6c55f3c20/nihms465026f1.jpg

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