先天性心脏病患儿坏死性小肠结肠炎的肠道位置。
Intestinal location of necrotizing enterocolitis among infants with congenital heart disease.
机构信息
Section for Perinatal Research, The Ohio State University of College and Medicine, Columbus, OH, USA.
出版信息
J Perinatol. 2013 Oct;33(10):783-5. doi: 10.1038/jp.2013.49. Epub 2013 May 2.
OBJECTIVE
To determine whether differences exist in the location of necrotizing enterocolitis (NEC) in infants with congenital heart disease (CHD) versus those without CHD.
STUDY DESIGN
Retrospective cohort study utilizing 11 years of patient data. Inclusion criterion was surgical exploration for NEC. Presence or absence of CHD was determined. Surgical and/or pathology reports were reviewed to identify the location of NEC. Data were analyzed by t-tests and χ(2) analyses.
RESULT
One hundred and sixty-seven patients met the inclusion criteria. CHD infants had a higher percentage of mortality. There was no difference in the location of NEC between non-CHD and CHD patients, with the predominant location being the small intestine in both. In addition, there was no difference in the location of NEC between preterm non-CHD patients and full-term CHD patients with the small intestine again being the primary site.
CONCLUSION
Despite differences in gestational age between non-CHD and CHD patients, the location of NEC in these infants did not differ.
目的
确定患有先天性心脏病（CHD）的婴儿与不患有 CHD 的婴儿的坏死性小肠结肠炎（NEC）的位置是否存在差异。
研究设计
利用 11 年的患者数据进行回顾性队列研究。纳入标准为手术探查 NEC。确定是否存在 CHD。审查手术和/或病理报告以确定 NEC 的位置。通过 t 检验和 χ(2)分析进行数据分析。
结果
167 名患者符合纳入标准。患有 CHD 的婴儿死亡率更高。非 CHD 与 CHD 患者的 NEC 位置无差异，两者的主要部位均为小肠。此外，非 CHD 的早产儿和 CHD 的足月儿的 NEC 位置也无差异，小肠仍然是主要部位。
结论
尽管非 CHD 和 CHD 患者的胎龄存在差异，但这些婴儿的 NEC 位置没有差异。
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