James L. Winkle College of Pharmacy, University of Cincinnati, Cincinnati, OH 45236, USA.
J Am Pharm Assoc (2003). 2013 Jan-Feb;53(1):22-9. doi: 10.1331/JAPhA.2013.11176.
To develop, implement, and evaluate a depression screening program performed by pharmacists in the community setting; to determine the ability of this screening to identify and refer patients with symptoms of depression; and to determine whether physician referral results in initiation or modification of treatment.
Prospective study.
32 locations of a large grocery chain pharmacy in the Cincinnati and Dayton, OH, area from February 8, 2010, to March 30, 2011.
3,726 patients 18 years or older.
Patients were screened for depression using the Patient Health Questionnaire (PHQ). Patients who screened positive on the two-item PHQ (PHQ-2) then were given the nine-item PHQ (PHQ-9). Patients who screened positive on the PHQ-9 were referred to their physician. Pharmacists followed up with these patients to determine the action that was taken following the screening.
Number of patients with a positive PHQ-9, number of patients referred to their physician, and number of patients for whom treatment was initiated or modified as a result of screening.
3,726 patients were screened for depression by pharmacists during the study period. A total of 67 (1.8%) patients screened positive on the PHQ-2. Of the patients who completed the PHQ-9, approximately 25% met the criteria for consideration of diagnosis and were referred to their physician. Five patients presented with suicidal thoughts and were referred for urgent treatment. Approximately 60% of patients with a positive PHQ-9 had initiated or modified treatment at the time of follow-up.
A screening program for depression was successfully developed and implemented in the community pharmacy setting. Using the PHQ, pharmacists were able to quickly identify undiagnosed patients with symptoms of depression. The majority of patients with a positive screening had initiated or modified treatment at the time of follow-up.
在社区环境中由药剂师开发、实施和评估抑郁筛查计划；确定该筛查在识别和转介有抑郁症状的患者方面的能力；并确定医生转介是否会导致开始或修改治疗。
前瞻性研究。
俄亥俄州辛辛那提和代顿地区的一家大型连锁杂货店的 32 个地点，时间为 2010 年 2 月 8 日至 2011 年 3 月 30 日。
3726 名 18 岁或以上的患者。
患者使用患者健康问卷（PHQ）进行抑郁筛查。在两项 PHQ（PHQ-2）上呈阳性的患者随后接受了九项 PHQ（PHQ-9）。在 PHQ-9 上呈阳性的患者被转介给他们的医生。药剂师对这些患者进行随访，以确定筛查后采取的行动。
PHQ-9 呈阳性的患者人数、转介给医生的患者人数以及因筛查而开始或修改治疗的患者人数。
在研究期间，共有 3726 名患者接受了药剂师的抑郁筛查。共有 67 名（1.8%）患者在 PHQ-2 上呈阳性。在完成 PHQ-9 的患者中，约 25%符合考虑诊断的标准，并被转介给他们的医生。有 5 名患者出现自杀念头，并被转介接受紧急治疗。在随访时，约 60%PHQ-9 呈阳性的患者已开始或修改治疗。
在社区药房环境中成功开发并实施了抑郁筛查计划。药剂师使用 PHQ 能够快速识别出未经诊断的有抑郁症状的患者。大多数阳性筛查患者在随访时已开始或修改治疗。
