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血管介入放射学的变化面貌:药物治疗和分子成像的未来作用。

The changing face of vascular interventional radiology: the future role of pharmacotherapies and molecular imaging.

机构信息

Department of Radiology, Oxford University Hospitals, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK.

出版信息

Cardiovasc Intervent Radiol. 2013 Aug;36(4):904-12. doi: 10.1007/s00270-013-0621-3. Epub 2013 May 2.

DOI:10.1007/s00270-013-0621-3
PMID:23636247
Abstract

Interventional radiology has had to evolve constantly because there is the ever-present competition and threat from other specialties within medicine, surgery, and research. The development of new technologies, techniques, and therapies is vital to broaden the horizon of interventional radiology and to ensure its continued success in the future. In part, this change will be due to improved chronic disease prevention altering what we treat and in whom. The most important of these strategies are the therapeutic use of statins, Beta-blockers, angiotensin-converting enzyme inhibitors, and substances that interfere with mast cell degeneration. Molecular imaging and therapeutic strategies will move away from conventional techniques and nano and microparticle molecular technology, tissue factor imaging, gene therapy, endothelial progenitor cells, and photodynamic therapy will become an important part of interventional radiology of the future. This review looks at these new and exciting technologies.

摘要

介入放射学必须不断发展,因为它始终面临着来自医学、外科和研究领域的其他专业的竞争和威胁。新技术、技术和疗法的发展对于拓宽介入放射学的视野并确保其未来的持续成功至关重要。在某种程度上,这种变化将归因于改善慢性病预防,改变我们的治疗对象和治疗方法。其中最重要的策略是他汀类药物、β受体阻滞剂、血管紧张素转换酶抑制剂和干扰肥大细胞退化物质的治疗用途。分子成像和治疗策略将脱离传统技术,纳米和微粒分子技术、组织因子成像、基因治疗、内皮祖细胞和光动力疗法将成为未来介入放射学的重要组成部分。这篇综述探讨了这些新的令人兴奋的技术。

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