Abbas Mujjahid, Cumella Lindsay, Zhang Yang, Choi Jenny, Vemulapalli Pratibha, Melvin W Scott, Camacho Diego
Montefiore Institute for Minimally Invasive Surgery, Montefiore Medical Center, 3400 Bainbridge Avenue, MAP 4, Bronx, NY, 104647, USA.
Department of Surgery, Albert Einstein College of Medicine, 3400 Bainbridge Avenue, MAP 4, Bronx, NY, 104647, USA.
Obes Surg. 2015 Dec;25(12):2251-6. doi: 10.1007/s11695-015-1712-9.
The proportion of population older than 60 years is rapidly increasing. The majority of this older population suffers from multiple comorbid conditions including obesity. Non-surgical means of weight loss do not offer a predictable solution. Surgical interventions seem to be the most promising solution for the obesity problem, but there is a relative lack of data in literature regarding bariatric procedures in older populations.
Our study aims to evaluate the safety and efficacy of bariatric surgery in patients older than 60 years of age, to determine the weight loss, rate of operation-related complications, and impacts of surgery on comorbid conditions, and to compare the effectiveness of bariatric surgery in older patients to the effectiveness of bariatric surgery for the general population at Montefiore Medical Center.
A retrospective review of patients' medical records were used to collect data to create databases to identify patients older than 60 years age who underwent bariatric surgery procedures spanning a 4-year period between January 2009 and October 2013. Data reviewed included age, sex, height, pre-operative weight, and body mass index (BMI), presence of obesity-related comorbid conditions, procedures performed, mortality, immediate or delayed complications, length of follow-up, excess weight lost, BMI points lost, percent of excess weight loss (%EWL), hemoglobin Alc (HgbA1c), and effects on obesity-related comorbid conditions. The percent of excess weight loss and number of complications within the older patient group were compared to the general population, which consists of patients between the ages of 22 and 59.
Ninety-eight patients were identified. Seven patients did not follow up at any time period, and the eight patients who had laparoscopic adjustable gastric band (LAGB) were also excluded due to insufficient data. Overall, 83 patients who were above the age of 60 were examined; 30 patients had laparoscopic sleeve gastrectomy (LSG), and 53 patients underwent laparoscopic Roux-en-Y gastric bypass (LRYGB). The average patient age was 63.4 years, the average pre-operative weight was 122.3 kg, and the average excess body weight was 54.8 kg. The pre-existing comorbid conditions included 90.4 % hypertension (HTN), 63.9 % diabetes mellitus (DM), 50.6 % hyperlipidemia (HL), 34.9 % obstructive sleep apnea (OSA), and 30.1 % asthma. The average %EWL at 3 months, 6 months, and 12 months was 37.0, 51.3, and 65.2 %, respectively. A significant proportion of patients reported resolution or improvement in comorbid conditions. When results were compared to the general, population there was no significant difference in the number of complications that occurred within each of the two groups. The difference in %EWL at the 12-month follow-up was not statistically significant between the general population and the older patients, which suggests that both groups lost a similar amount of weight and that bariatric surgery on patients who are above the age of 60 is effective.
Bariatric surgery can be safe and effective for patients older than 60 years of age with a low morbidity and mortality; the weight loss and improvement in comorbidities in older patients were clinically significant. When compared to the general population, there was no statistically significant difference in the average %EWL at 12 months or the number of complications due to surgery. Long-term effects of such interventions will need further studies and investigations.
60岁以上人口比例正在迅速增长。这一老年人群中的大多数患有包括肥胖症在内的多种合并症。非手术减肥方法并不能提供可预测的解决方案。手术干预似乎是解决肥胖问题最有前景的方法,但关于老年人群减肥手术的文献数据相对较少。
我们的研究旨在评估60岁以上患者减肥手术的安全性和有效性,确定体重减轻情况、手术相关并发症发生率以及手术对合并症的影响,并比较蒙特菲奥里医疗中心老年患者减肥手术的有效性与普通人群减肥手术的有效性。
回顾性审查患者病历以收集数据,创建数据库来识别2009年1月至2013年10月这4年间接受减肥手术的60岁以上患者。审查的数据包括年龄、性别、身高、术前体重和体重指数(BMI)、肥胖相关合并症的存在情况、所进行的手术、死亡率、即时或延迟并发症、随访时间、体重减轻量、BMI降低值、超重减轻百分比(%EWL)、糖化血红蛋白(HgbA1c)以及对肥胖相关合并症的影响。将老年患者组的超重减轻百分比和并发症数量与普通人群(年龄在22至59岁之间的患者)进行比较。
共识别出98例患者。7例患者在任何时间段均未进行随访,并且由于数据不足,8例接受腹腔镜可调节胃束带术(LAGB)的患者也被排除。总体而言,对83例60岁以上患者进行了检查;30例患者接受了腹腔镜袖状胃切除术(LSG),53例患者接受了腹腔镜Roux-en-Y胃旁路术(LRYGB)。患者平均年龄为63.4岁,术前平均体重为122.3千克,平均超重为54.8千克。既往合并症包括90.4%的高血压(HTN)、63.9%的糖尿病(DM)、50.6%的高脂血症(HL)、34.9%的阻塞性睡眠呼吸暂停(OSA)和30.1%的哮喘。3个月、6个月和12个月时的平均%EWL分别为37.0%、51.3%和65.2%。相当一部分患者报告合并症得到缓解或改善。当将结果与普通人群比较时,两组中发生的并发症数量没有显著差异。普通人群和老年患者在12个月随访时的%EWL差异无统计学意义,这表明两组体重减轻量相似,且60岁以上患者的减肥手术是有效的。
减肥手术对于60岁以上患者可能是安全有效的,发病率和死亡率较低;老年患者的体重减轻和合并症改善具有临床意义。与普通人群相比,12个月时的平均%EWL或手术相关并发症数量没有统计学显著差异。此类干预措施 的长期影响需要进一步研究和调查。