耐阿莫西林-克拉维酸的大肠杆菌的流行病学和临床复杂性。
Epidemiological and clinical complexity of amoxicillin-clavulanate-resistant Escherichia coli.
机构信息
Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario Virgen Macarena, Seville, Spain.
出版信息
J Clin Microbiol. 2013 Jul;51(7):2414-7. doi: 10.1128/JCM.00999-13. Epub 2013 May 1.
Abstract
Two hundred twelve patients with colonization/infection due to amoxicillin-clavulanate (AMC)-resistant Escherichia coli were studied. OXA-1- and inhibitor-resistant TEM (IRT)-producing strains were associated with urinary tract infections, while OXA-1 producers and chromosomal AmpC hyperproducers were associated with bacteremic infections. AMC resistance in E. coli is a complex phenomenon with heterogeneous clinical implications.
摘要
对 212 例因耐阿莫西林克拉维酸（AMC）的大肠埃希菌定植/感染的患者进行了研究。产 OXA-1 和抑制剂耐药 TEM（IRT）的菌株与尿路感染有关，而产 OXA-1 的菌株和染色体 AmpC 超产株与菌血症感染有关。大肠埃希菌对 AMC 的耐药性是一种具有不同临床意义的复杂现象。
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