Dharmasena Aruna, Wallis Simon
Department of Ophthalmology, Royal Bolton Hospital Foundation Trust, Bolton, BL4 0JR, United Kingdom.
Int J Ophthalmol. 2013 Apr 18;6(2):246-50. doi: 10.3980/j.issn.2222-3959.2013.02.26. Print 2013.
To analyse previous literature and to formulate a management strategy for iris microhaemangiomas (IMH).
A review of the literature in English language articles on IMH.
Thirty five English language articles fulfilled the criteria for inclusion to the study and based on the contents on these articles a management strategy was formulated. Age at presentation ranged from 42 to 80 years with no sex or racial predisposition. Most patients with IMH have no systemic disease but a higher incidence had been reported in patients with diabetes mellitus, myotonic dystrophy, chronic obstructive pulmonary disease (COPD) and several other systemic and ophthalmic co-morbidities. Most patients remained asymptomatic until they experienced a sudden blurring of vision due to a hyphaema. Some patients only develop a self-limiting single episode of hyphaema and therefore the laser or surgical photocoagulation of iris should be reserved for the cases complicated with recurrent hyphaema. In some patients, several laser photocoagulation sessions may be needed and the recurrent iris vascular tufts may require more aggressive treatment. Iris fluorescein angiography (IFA) is useful in identifying the true extent of the disease and helps to improve the precision of the laser treatment. Surgical excision (iridectomy) should only be considered in patients who fail to respond to repeated laser treatment. In some cases IMHs has been initially misdiagnosed as amaurosis fugax, iritis and Posner-Schlossman syndrome.
Owing to its scarcity, there is no good quality scientific evidence to support the management of IMH. The authors discuss the various treatment options and present a management strategy based on the previous literature for the management for this rare condition and its complications.
分析既往文献并制定虹膜微血管瘤(IMH)的管理策略。
对关于IMH的英文文献进行综述。
35篇英文文章符合纳入本研究的标准,并基于这些文章的内容制定了管理策略。就诊年龄范围为42至80岁,无性别或种族倾向。大多数IMH患者无全身性疾病,但据报道糖尿病、强直性肌营养不良、慢性阻塞性肺疾病(COPD)及其他一些全身性和眼科合并症患者的发病率较高。大多数患者在因前房积血出现视力突然模糊之前一直无症状。一些患者仅发生一次自限性前房积血,因此虹膜激光或手术光凝应仅用于并发反复前房积血的病例。在一些患者中,可能需要多次激光光凝治疗,而复发性虹膜血管丛可能需要更积极的治疗。虹膜荧光血管造影(IFA)有助于确定疾病的真实范围,并有助于提高激光治疗的精确性。仅在对反复激光治疗无反应的患者中考虑手术切除(虹膜切除术)。在某些情况下,IMH最初被误诊为一过性黑矇、虹膜炎和波斯纳 - 施洛斯曼综合征。
由于其罕见性,尚无高质量科学证据支持IMH的管理。作者讨论了各种治疗选择,并基于既往文献提出了针对这种罕见疾病及其并发症的管理策略。