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一名视网膜分支静脉阻塞患者,玻璃体内注射贝伐单抗联合加压包扎成功治疗急性虹膜血管簇状出血。

Acute iris vascular tuft hemorrhage treated successfully with intravitreal bevacizumab and pressure patching in a patient with branch retinal vein occlusion.

作者信息

Polski Ashley, Kennedy Brandon, Bair Christopher, Simpson Rachel

机构信息

John A. Moran Eye Center, The University of Utah, Salt Lake City, UT, USA.

出版信息

Am J Ophthalmol Case Rep. 2022 Dec 13;29:101780. doi: 10.1016/j.ajoc.2022.101780. eCollection 2023 Mar.

DOI:10.1016/j.ajoc.2022.101780
PMID:36582845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9792291/
Abstract

PURPOSE

To report the presentation and management of active iris vascular tuft (IVT) hemorrhage and spontaneous hyphema in an eye with previous branch retinal vein occlusion (BRVO).

OBSERVATIONS

A 74-year-old male with a history of BRVO in the left eye presented with spontaneous hyphema and blurred vision. Clinical examination confirmed the presence of an actively bleeding IVT at the pupillary margin in the left eye. Sustained hemostasis was achieved following intravitreal bevacizumab injection and pressure patching of the eye.

CONCLUSIONS AND IMPORTANCE

This is the first case report to demonstrate pressure patching as a non-invasive, effective method of achieving hemostasis in the acute setting of IVT hemorrhage. Intravitreal vascular endothelial growth factor antagonists such as bevacizumab may also be useful in decreasing the risk of IVT hemorrhage in eyes with chronic ischemia, although further investigation is warranted.

摘要

目的

报告既往有视网膜分支静脉阻塞(BRVO)的眼内活动性虹膜血管簇(IVT)出血和自发性前房积血的表现及处理。

观察结果

一名74岁男性,左眼有BRVO病史,出现自发性前房积血和视力模糊。临床检查证实左眼瞳孔边缘存在活动性出血的IVT。玻璃体腔内注射贝伐单抗并对眼睛进行加压包扎后实现了持续止血。

结论与意义

这是首例证明加压包扎作为IVT出血急性期实现止血的非侵入性有效方法的病例报告。玻璃体腔内血管内皮生长因子拮抗剂如贝伐单抗在降低慢性缺血性眼病IVT出血风险方面可能也有用,尽管仍需进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f583/9792291/85ac0d30c902/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f583/9792291/9577c978d24e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f583/9792291/85ac0d30c902/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f583/9792291/9577c978d24e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f583/9792291/85ac0d30c902/gr2.jpg

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本文引用的文献

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Indian J Ophthalmol. 2019 Dec;67(12):2080-2082. doi: 10.4103/ijo.IJO_1200_19.
2
Active iris vascular tufts bleeding successfully treated with argon laser photocoagulation.氩激光光凝成功治疗活动性虹膜血管簇出血。
Eur J Ophthalmol. 2018 Mar;28(2):241-242. doi: 10.5301/ejo.5001021.
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Iris microhemangiomatosis with videographically documented active bleeding and vision loss.
虹膜微血管瘤病,伴有影像学记录的活动性出血和视力丧失。
JAMA Ophthalmol. 2013 Dec;131(12):1649-51. doi: 10.1001/jamaophthalmol.2013.6211.
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Iris microhaemangioma: a management strategy.虹膜微血管瘤:一种治疗策略。
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Retinal vein occlusions: The potential impact of a dysregulation of the retinal veins.视网膜静脉阻塞:视网膜静脉调节异常的潜在影响。
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Spontaneous hyphaema from pupillary vascular tufts in a patient with branch retinal vein occlusion.一名视网膜分支静脉阻塞患者因瞳孔血管丛导致的自发性前房积血。
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