有机磷中毒所致急性肾衰竭。
Organophosphate poisoning-induced acute renal failure.
作者信息
Cavari Yuval, Landau Daniel, Sofer Shaul, Leibson Tom, Lazar Isaac
机构信息
Pediatric Intensive Care Unit, Department of Pediatrics A, Soroka Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Israel.
出版信息
Pediatr Emerg Care. 2013 May;29(5):646-7. doi: 10.1097/PEC.0b013e31828e9e45.
BACKGROUND
Acute kidney injury as a direct complication of organophosphate poisoning has rarely been described and its etiology is unclear.
CASE
A 17-year-old adolescent girl was admitted to the pediatric intensive care unit after a suicidal attempt with chlorpyrifos, an organophosphate insecticide compound. The patient developed acute kidney injury followed by renal failure, necessitating renal replacement therapy. She was treated with continuous venovenous hemofiltration with full resolution of her renal function.
CONCLUSIONS
Organophosphate poisoning can lead to renal failure, which, with proper treatment, may be reversible but, if left unattended, might aggravate the clinical course of the disease. Physicians should be aware of this rare complication.
背景
急性肾损伤作为有机磷中毒的直接并发症鲜有报道，其病因尚不清楚。
病例
一名17岁少女因企图自杀服用毒死蜱（一种有机磷杀虫剂化合物）后被收入儿科重症监护病房。该患者出现急性肾损伤，随后发展为肾衰竭，需要进行肾脏替代治疗。她接受了连续性静脉-静脉血液滤过治疗，肾功能完全恢复。
结论
有机磷中毒可导致肾衰竭，经适当治疗可能可逆，但如果不加以处理，可能会加重疾病的临床进程。医生应意识到这种罕见的并发症。
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