Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Clin Nucl Med. 2013 Jun;38(6):480-1. doi: 10.1097/RLU.0b013e31828e98dc.
A woman with bilateral breast cancer treated with bilateral mastectomies, implant reconstructions, chemotherapy, and hormonal therapy underwent FDG PET/CT imaging. Imaging demonstrated sternal, nodal, and lung lesions which were stable or slowly increasing, as well as a parasternal chest wall mass which was enlarging much more rapidly and was excised. Pathology of the chest wall mass demonstrated only benign soft tissue with fat necrosis and foreign body giant cell reaction, without evidence of malignancy or implant rupture. This case demonstrates how a benign FDG-avid foreign body reaction, induced by an intact breast prosthesis, could easily be mistaken for malignancy.
一位双侧乳腺癌女性患者接受了双侧乳房切除术、植入物重建、化疗和激素治疗，随后进行了 FDG PET/CT 成像。成像显示胸骨、淋巴结和肺部病变稳定或缓慢增加，以及胸骨旁胸壁肿块快速增大并被切除。胸壁肿块的病理显示仅为良性软组织，伴有脂肪坏死和异物巨细胞反应，没有恶性或植入物破裂的证据。本例表明，完整的乳房假体引起的良性 FDG 摄取的异物反应很容易被误诊为恶性肿瘤。
