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PET/CT上18F-FDG摄取增加的乳腺病变谱

Spectrum of the Breast Lesions With Increased 18F-FDG Uptake on PET/CT.

作者信息

Dong Aisheng, Wang Yang, Lu Jianping, Zuo Changjing

机构信息

From the Departments of *Nuclear Medicine, †Pathology, and ‡Radiology, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.

出版信息

Clin Nucl Med. 2016 Jul;41(7):543-57. doi: 10.1097/RLU.0000000000001203.

DOI:10.1097/RLU.0000000000001203
PMID:26975010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4902325/
Abstract

Interpretation of F-FDG PET/CT studies in breast is challenging owing to nonspecific FDG uptake in various benign and malignant conditions. Benign conditions include breast changes in pregnancy and lactation, gynecomastia, mastitis, fat necrosis, fibroadenoma, intraductal papilloma, and atypical ductal hyperplasia. Among malignancies, invasive ductal carcinoma and invasive lobular carcinoma are common histological types of breast carcinoma. Rarely, other unusual histological types of breast carcinomas (eg, intraductal papillary carcinoma, invasive micropapillary carcinoma, medullary carcinoma, mucinous carcinoma, and metaplastic carcinoma), lymphoma, and metastasis can be the causes. Knowledge of a wide spectrum of hypermetabolic breast lesions on FDG PET/CT is essential in accurate reading of FDG PET/CT. The purpose of this atlas article is to demonstrate features of various breast lesions encountered at our institution, both benign and malignant, which can result in hypermetabolism on FDG PET/CT imaging.

摘要

由于在各种良性和恶性情况下FDG摄取不具有特异性，因此解读乳腺的F-FDG PET/CT研究具有挑战性。良性情况包括妊娠和哺乳期的乳腺变化、男性乳房发育、乳腺炎、脂肪坏死、纤维腺瘤、导管内乳头状瘤和非典型导管增生。在恶性肿瘤中，浸润性导管癌和浸润性小叶癌是乳腺癌常见的组织学类型。其他罕见的不寻常组织学类型的乳腺癌（如导管内乳头状癌、浸润性微乳头状癌、髓样癌、黏液癌和化生癌）、淋巴瘤和转移瘤也可能是病因。了解FDG PET/CT上广泛的高代谢乳腺病变对于准确解读FDG PET/CT至关重要。本图谱文章的目的是展示我们机构遇到的各种乳腺病变（包括良性和恶性）的特征，这些病变可导致FDG PET/CT成像上的高代谢。

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