Department of Internal Medicine, Maimonides Medical Center, 1016 50th Street Apt 2C, Brooklyn, NY 11219, USA.
J Thromb Thrombolysis. 2013 May;35(4):463-8. doi: 10.1007/s11239-013-0928-6.
Surgical aortic valve replacement improves morbidity and mortality in patients with severe aortic valve stenosis and is treatment of choice for symptomatic patients. As high, one-third of patients with severe AS are considered inoperable due to associated high surgical risk. Recently, transcatheter aortic valve implantation (TAVI) has been demonstrated to improve survival, quality of life, and functional status in patients who are considered inoperable due to high risk of surgery. However, access site and non-access site bleeding are major procedural complications after TAVI and are associated with worse clinical outcomes. In this review, we systematically study the access site complication associated with TAVI and approaches that can minimize these complications.
外科主动脉瓣置换术可改善重度主动脉瓣狭窄患者的发病率和死亡率,是有症状患者的治疗选择。由于高手术风险,约三分之一的重度 AS 患者被认为无法手术。最近,经导管主动脉瓣植入术(TAVI)已被证明可改善因手术风险高而被认为无法手术的患者的生存率、生活质量和功能状态。然而,TAVI 后的入路部位和非入路部位出血是主要的手术并发症,并与更差的临床结局相关。在这篇综述中,我们系统地研究了与 TAVI 相关的入路部位并发症及可尽量减少这些并发症的方法。