Passamonti S, Battiston L, Sottocasa G L
Dipartimento di Biochimica Biofisica e, Chimica delle Macromolecole, Università degli Studi di Trieste, Italy.
Biochim Biophys Acta. 1990 Jun 27;1025(2):122-6. doi: 10.1016/0005-2736(90)90088-6.
Specific guanido group reagents inhibit bilitranslocase transport activity in rat liver plasma membrane vesicles. Their reaction is shown to be affected by sulfobromophthalein, Thymol blue and bilirubin, which are translocated by bilitranslocase across the plasma membrane. It is concluded that the transport function of bilitranslocase depends on arginine residues, which are involved in the interaction with the molecules to be translocated.
特定的胍基试剂可抑制大鼠肝细胞膜囊泡中的胆红素转运酶转运活性。已表明它们的反应会受到磺溴酞、百里酚蓝和胆红素的影响，这些物质可通过胆红素转运酶跨细胞膜转运。得出的结论是，胆红素转运酶的转运功能取决于精氨酸残基，这些残基参与与待转运分子的相互作用。
