Heart Research Institute, Sir Charles Gairdner Hospital, Perth, WA, Australia.
Med J Aust. 2013 May 6;198(8):419-22. doi: 10.5694/mja12.10922.
While the Australian National Health and Medical Research Council guideline document of 2009 on reducing health risks from drinking alcohol provided sensible advice for public policy on alcohol, it appeared to dismiss the cardiovascular benefits of low to moderate consumption. Undue prominence was given to a hypothesis from a single research group that the well documented J-curve relationship of lower risk of ischaemic heart disease events with low to moderate intake alcohol consumption may have been due to a misclassification of drinking patterns. The misclassification hypothesis suggested that the higher risks among abstainers may have been due to the inclusion of high-risk subjects who had become abstainers later in life. Recent studies have separated recent abstainers from lifetime abstainers and the misclassification hypothesis has not been confirmed as an explanation for the J-shaped curve. The J-shaped relationship between alcohol consumption and cardiovascular risk has been studied and confirmed in multiple studies; while it complicates the formulation of public policy on alcohol consumption, it cannot be dismissed.
2009 年，澳大利亚国家卫生和医学研究委员会发布了一份关于减少饮酒健康风险的指导文件，为制定关于饮酒的公共政策提供了合理建议，但该文件似乎忽视了低至中度饮酒对心血管的益处。该文件过分强调了来自一个研究小组的假设，即众所周知的缺血性心脏病事件风险与低至中度饮酒摄入量之间的“J 型曲线关系”可能是由于对饮酒模式的错误分类。该错误分类假设表明，不饮酒者的风险较高可能是由于包括后来戒酒的高风险人群。最近的研究将近期戒酒者与终生戒酒者分开，错误分类假设并未被证实可以解释 J 型曲线。饮酒与心血管风险之间的 J 型关系已在多项研究中进行了研究和证实；虽然这使得制定关于饮酒的公共政策变得复杂，但不能忽视这一关系。
