Anbar R, Beloosesky Y, Cohen J, Madar Z, Weiss A, Theilla M, Koren Hakim T, Frishman S, Singer P
Nutrition Unit, Rabin Medical Center, Petah Tikva, Israel; School of Nutritional Sciences, The Robert H Smith Faculty of Agriculture, Food and Environmental Quality Sciences, Hebrew University, Jerusalem, Israel.
Department of Geriatrics, Rabin Medical Center, Petah Tikva and Sackler School of Medicine, Tel Aviv University, Israel.
Clin Nutr. 2014 Feb;33(1):23-8. doi: 10.1016/j.clnu.2013.03.005. Epub 2013 Apr 1.
BACKGROUND & AIMS: Optimizing nutritional intake has been recommended for geriatric patients undergoing hip-fracture surgery. Whether nutritional support guided by repeated measurements of resting energy requirements (REE) improves outcomes in these patients is not known.
A randomized, controlled, unblinded, prospective, cohort study comparing provision of energy with a goal determined by repeated REE measurements using indirect calorimetry, with no intervention. Oral nutritional supplements were started 24 h after surgery and the amount adjusted to make up the difference between energy received from hospital food and measured energy expenditure.
50 Geriatric patients were included in the study. Patients in the intervention group (n = 22) received significantly higher daily energy intake than the control group (n = 28) (1121.3 ± 299.0 vs. 777.1 ± 301.2 kcal, p = 0.001). This was associated with a significantly less negative cumulative energy balance (-1229.9 ± 1763 vs. -4975.5 ± 4368 kcal, p = 0.001). A significant negative correlation was found between the cumulative energy balance and total complication rate (r = -0.417, p = 0.003) as well as for length of hospital stay (r = -0.282, p = 0.049).
We have demonstrated that nutritional support actively supervised by a dietician and guided by repeated measurements of REE was achievable and improved outcomes in geriatric patients following surgery for hip fractures. Clinicaltrials.gov Identifier: NCT017354435.
对于接受髋部骨折手术的老年患者,建议优化营养摄入。目前尚不清楚通过重复测量静息能量需求(REE)来指导营养支持是否能改善这些患者的预后。
一项随机、对照、非盲、前瞻性队列研究,比较使用间接测热法通过重复测量REE确定目标来提供能量与不进行干预的情况。术后24小时开始口服营养补充剂,并调整剂量以弥补医院食物提供的能量与测量的能量消耗之间的差异。
50名老年患者纳入研究。干预组(n = 22)患者的每日能量摄入量显著高于对照组(n = 28)(1121.3±299.0 vs. 777.1±301.2千卡,p = 0.001)。这与显著减少的负累积能量平衡相关(-1229.9±1763 vs. -4975.5±4368千卡,p = 0.001)。累积能量平衡与总并发症发生率(r = -0.417,p = 0.003)以及住院时间(r = -0.282,p = 0.049)之间存在显著负相关。
我们已经证明,由营养师积极监督并通过重复测量REE指导的营养支持在髋部骨折手术后的老年患者中是可行的,并改善了预后。Clinicaltrials.gov标识符:NCT017354435。