Department of Urology, Columbia University Medical Center, New York Presbyterian Hospital, New York, NY, USA.
Urology. 2013 Jul;82(1):231-6. doi: 10.1016/j.urology.2013.02.046. Epub 2013 May 2.
To assess functional outcomes and complications of ureteroneocystotomies (UNCs) with or without psoas hitch or Boari flap in the reconstruction and repair of the ureter.
We reviewed a consecutive series of patients that underwent open ureteral reconstruction for ureteral obstruction or injury. Underlying ureteral disorder, preoperative and postoperative estimated glomerular filtration rate (eGFR), and imaging studies regarding resolution of hydronephrosis were assessed.
A total of 100 ureteral reimplantations performed at our institution from November 1986 to August 2012 were identified: 24 primary ureteroneocystotomies, 58 with psoas hitch, and 18 with Boari flap. Median follow-up was 48.7 months (range 12.3-253 months). The most common underlying disorder was ureteral transitional cell cancer (TCC). Men were found to have more frequent underlying chronic ureteral disorders with chronic renal failure when compared to women. Ureteral stents were placed in 81% and were removed after a median of 33 days (range 2-161 days). Resolution of hydronephrosis was noted in 81% of the patients. The eGFR deteriorated significantly over time only in male patients (P = .001). Postoperative complications included stent-related dysuria, urinary tract infection, and contrast-extravasation on cystogram necessitating prolonged urethral and ureteral catheter drainage.
Excellent functional outcome without significant morbidity associated with ureteral reimplantation/reconstruction was achieved. Despite resolution of hydronephrosis in the vast majority of patients, those with chronic underlying ureteral disorder and renal failure did not show improvement of their eGFR.
评估在重建和修复输尿管时,输尿管吻合术(UNC)联合或不联合腰大肌悬带或 Boari 皮瓣的功能结果和并发症。
我们回顾性分析了在我院接受开放输尿管重建术以治疗输尿管梗阻或损伤的连续系列患者。评估了基础输尿管疾病、术前和术后估算肾小球滤过率(eGFR)以及关于肾积水缓解的影像学研究。
在我院,1986 年 11 月至 2012 年 8 月共进行了 100 例输尿管再植入术:24 例原发性输尿管吻合术、58 例联合腰大肌悬带术和 18 例联合 Boari 皮瓣术。中位随访时间为 48.7 个月(范围 12.3-253 个月)。最常见的基础疾病是输尿管移行细胞癌(TCC)。与女性相比,男性更常患有基础慢性输尿管疾病和慢性肾衰竭。81%的患者留置输尿管支架,中位留置时间为 33 天(范围 2-161 天)。81%的患者肾积水得到缓解。只有男性患者的 eGFR 随时间显著恶化(P=0.001)。术后并发症包括支架相关排尿困难、尿路感染和膀胱造影显示对比剂外渗,需要长时间留置尿道和输尿管导管引流。
实现了输尿管再植入/重建后无明显发病率但具有良好功能结果。尽管大多数患者肾积水得到缓解,但那些患有慢性基础输尿管疾病和肾衰竭的患者的 eGFR 并未改善。