Mirzazadeh Majid, Badran Merhan, Smith Whitney
Department of Urology, Wake Forest University School of Medicine Wake Forest Baptist Medical Center Winston-Salem North Carolina USA.
Department of Urology Thomas Jefferson University Philadelphia Pennsylvania USA.
BJUI Compass. 2024 Feb 20;5(4):447-459. doi: 10.1002/bco2.327. eCollection 2024 Apr.
To present an alternative technique called pseudo-flap for reconstructing long ureteral defects as an alternative to Boari flap. Despite being used for more than 70 years by urologists for tension-free reconstruction of distal and mid-ureteral defects, the Boari flap exhibits high complication rates, with an average of 27% (range 5.5%-30.4%). These complications arise from compromised blood supply, attributed to incisions made on all three sides of the flap and dependence on the flap base as the sole source of blood supply.
We retrospectively reviewed patients who underwent our modified technique by a single surgeon between 2008 and 2021. We used a semi-oblique cystotomy on the lowest part of the anterior and contralateral aspects of the bladder after complete release from adhesions and sacrificing the superior vesical pedicle, if necessary. The innovative part of the technique involved making short relaxing incisions at different levels on both sides of a pseudo-flap while pushing the bladder dome upward to reach the healthy ureter in a tension-free manner, followed by anastomosis with a non-refluxing or refluxing technique.
Fifteen patients underwent the pseudo-flap technique with a mean follow-up of 16.9 months. Four had prior radiation, three had hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis, and one had a ureteral stricture in a transplanted kidney. Eight procedures were performed during intraoperative consultations.Only one patient (7%) developed a major complication (Clavien-Dindo grade ≥2). This patient developed postoperative leak, and none developed obstructive hydronephrosis, suggesting stricture or flap ischemia. The mean length of the flap was 9.3 cm.
Our pseudo-flap technique has lower complication rates than the traditional Boari flap. It is not technically challenging, minimally compromises blood supply and is thus especially suitable for complex, highly morbid patients with decreased tissue vascularity, such as those with prior radiation and peritoneal carcinomatosis.
介绍一种名为假皮瓣的替代技术,用于重建长段输尿管缺损,作为Boari皮瓣的替代方法。尽管泌尿外科医生使用Boari皮瓣进行远端和中段输尿管缺损的无张力重建已有70多年,但该皮瓣的并发症发生率较高,平均为27%(范围5.5%-30.4%)。这些并发症源于血供受损,这归因于在皮瓣的三边进行切口以及依赖皮瓣基部作为唯一的血供来源。
我们回顾性分析了2008年至2021年间由一名外科医生实施我们改良技术的患者。在完全松解粘连并在必要时牺牲膀胱上蒂后,我们在膀胱前侧和对侧最低部位进行半斜切口膀胱切开术。该技术的创新之处在于,在将膀胱顶部向上推以无张力方式到达健康输尿管的同时,在假皮瓣两侧的不同水平进行短的松弛切口,然后采用抗反流或反流技术进行吻合。
15例患者接受了假皮瓣技术,平均随访16.9个月。4例患者曾接受过放疗,3例因腹膜癌接受过腹腔内热化疗(HIPEC),1例移植肾出现输尿管狭窄。8例手术在术中会诊时进行。只有1例患者(7%)发生了严重并发症(Clavien-Dindo分级≥2级)。该患者出现术后漏尿,无患者发生梗阻性肾积水,提示狭窄或皮瓣缺血。皮瓣的平均长度为9.3厘米。
我们的假皮瓣技术并发症发生率低于传统的Boari皮瓣。它在技术上没有挑战性,对血供的影响最小,因此特别适合组织血管减少的复杂、高风险患者,如那些曾接受过放疗和患有腹膜癌的患者。