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《苏格兰血液学2012:21世纪第二个十年的输血/移植医学》

Scotblood 2012: transfusion/transplant medicine in the 2nd decade of the 21st century.

作者信息

Colligan David, McGowan Neil, Seghatchian Jerard

机构信息

Scottish National Blood Transfusion Service, Edinburgh and Glasgow, United Kingdom.

出版信息

Transfus Apher Sci. 2013 Jun;48(3):415-20. doi: 10.1016/j.transci.2013.04.034. Epub 2013 May 2.

DOI:10.1016/j.transci.2013.04.034
PMID:23643474
Abstract

Transfusion medicine is a technology-based discipline, undergoing continual changes for improvement. It requires staff at all levels to be continually educated and trained in appropriate multidisciplinary skills, in line with the rapid developments in all areas of transfusion practice: from blood/organ collection, through processing and storage to the more advanced cellular and hospital-based transfusion/transplantation therapies. Whilst the majority of the challenges to improve hospital and general transfusion practice can be overcome through team work, education, timely objectives and perseverance, it is important to envisage opportunities for implementing digital technologies to reduce all of the applicable hazards associated with transfusion. These can vary widely from new and emerging pathogens to limitations of supply due to growing demographic changes in populations. In the first decade of 21st century we have already witnessed unprecedented advances in haematopoietic stem cell transplantation to minimise the toxicities of graft versus host disease (GvHD), and in cell therapy to explore immunotherapy against cancer and other malignant disorders. Today there are 1000 genome project hapmaps that only the extreme cost of their implementation to routine practices may limit. Transfusion medicine, like all disciplines of medicine, nevertheless, will face difficult choices between increasing healthcare technology and increasing worldwide health. Drs. Colligan and McGowan, the new lead organisers of this wonderful yearly educational programme have agreed to follow the previous organisers' strategy to make a summary report of their meeting to become available, through TRASCI to broader interested groups, with the sprit that "sharing is caring". The main highlights of the 2012 conference were: targeting transfusion practices in hospital, a continuing journey; emerging infections and the potential causes and possible remedial actions; building for the future; the challenging issues of donor recruitment/retention; and finally; the application of Information Technology as a decision making tool, utilising clinical audit monitoring to evaluate good practice. This year's conference also coincided with the retirement of Martin Bruce OBE, after his 41years distinguished career, who gave the most delightful and humorous talk of a" life time of learning" which delighted all the participants. Finally, 2012 also marked the retirements of the previous lead Scotblood organisers Prof. Robin Fraser and Dr. Hagop Bessos after over thirty years service to SNBTS, and to whom we would like to dedicate this meeting report and wish them a happy and healthy retirement. This commentary comprises summaries of the presentations, based in part on the abstracts provided by the speakers.

摘要

输血医学是一门以技术为基础的学科,它不断发展以求改进。随着输血实践各个领域的快速发展,从血液/器官采集、处理和储存到更先进的细胞及基于医院的输血/移植治疗,这要求各级工作人员不断接受适当的多学科技能教育和培训。虽然通过团队合作、教育、适时目标和坚持不懈,改善医院及一般输血实践中的大多数挑战都能克服,但设想实施数字技术以减少与输血相关的所有适用风险也很重要。这些风险范围广泛,从新出现的病原体到因人口结构变化导致的供应限制。在21世纪的第一个十年,我们已经见证了造血干细胞移植在将移植物抗宿主病(GvHD)毒性降至最低方面取得的前所未有的进展,以及细胞疗法在探索针对癌症和其他恶性疾病的免疫疗法方面的进展。如今有1000个基因组计划单倍型图谱,可能只是其实施到常规实践的极高成本限制了它们。然而,与所有医学学科一样,输血医学在增加医疗技术与增进全球健康之间将面临艰难抉择。本次精彩年度教育项目的新任牵头组织者科利根博士和麦高恩博士同意遵循前任组织者的策略,通过TRASCI向更广泛的感兴趣群体提供他们会议的总结报告,秉持“分享即关怀”的精神。2012年会议的主要亮点包括:针对医院输血实践,这是一个持续的过程;新出现的感染以及潜在原因和可能的补救措施;为未来建设;献血者招募/保留的挑战性问题;最后是将信息技术用作决策工具,利用临床审计监测来评估良好实践。今年的会议还恰逢马丁·布鲁斯OBE在其41年杰出职业生涯后退休,他发表了一场关于“一生学习”的极其愉快且幽默的演讲,令所有与会者都很高兴。最后,2012年也是前苏格兰血液制品组织牵头人罗宾·弗雷泽教授和哈戈普·贝索斯博士退休之年,他们为苏格兰国家血液输血服务中心服务了三十多年,我们谨将这份会议报告献给他们,并祝愿他们退休后幸福健康。本评论包含演讲内容的摘要,部分基于演讲者提供的摘要。

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