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10 年以上随访的全膝关节置换术的生存分析:一项包括 846 例病例的法国多中心全国性研究。

Survival analysis of total knee arthroplasty at a minimum 10 years' follow-up: a multicenter French nationwide study including 846 cases.

机构信息

Orthopedic Surgery Department, Sainte-Marguerite Hospital, Marseille University Hospitals, 270, boulevard Sainte-Marguerite, 13009 Marseille, France.

出版信息

Orthop Traumatol Surg Res. 2013 Jun;99(4):385-90. doi: 10.1016/j.otsr.2013.03.014. Epub 2013 May 2.

Abstract

INTRODUCTION

Survivorship for modern total knee arthroplasties (TKA) is not precisely known from large series, other than registries. The present retrospective study therefore analyzed 846 TKAs at a minimum 10 years' follow-up.

HYPOTHESIS

Ten-year survivorship for TKAs in a multicenter study exceeds 90%, independently of design and level of prosthetic constraint.

MATERIALS AND METHODS

Eight hundred and twenty-eight patients (846 TKAs) were assessed on the Knee Society score. Mean age was 71 years (range, 41-93 years); 274 males and 554 females (67%); 496 patients (60%) were active; diagnosis was principally osteoarthritis (n=752 [89%]). Most TKAs were cemented (n=704 [83%]), replacing the patella (n=668 [79%]) and sacrificed the posterior cruciate ligament (PCL) (n=707 [84%]), 65% being posterior-stabilized and 35% ultracongruent, with fixed (39%) or mobile bearing (61%).

RESULTS

At a minimum 10 years' follow-up, mean knee score rose from 35 (15-55) to 83 points (74-95), and functional score from 24 (5-45) to 74 points (60-90); mean flexion rose from 105° (25-125°) to 112° (25-125°). Mean hip-knee-ankle angle was 179.5° (169-189°). Sixty-three (7.5%) revision surgeries were required, mainly for loosening (n=18 [2%]) or infection (n=18 [1.8%]). Overall 10-year survivorship was 92% (95% CI: 0.90-0.94). There was no significant difference in survivorship according to implant design or PCL retention. Activity level correlated with revision rate; mechanical complications were more frequent in active and infectious complications in sedentary subjects. Revision was not more frequent in TKA aligned outside the 177-183° range.

DISCUSSION

Ten-year TKA survivorship was 92%, independently of design and level of mechanical stress. Revision was mainly for infection or loosening, and not for greater than 3° axis misalignment. Mechanical complications were more frequent in younger and more active subjects, for whom therefore other treatment options or technical improvements should be sought.

LEVEL OF EVIDENCE

Level IV. Retrospective study.

摘要

简介

现代全膝关节置换术(TKA)的生存率除了登记处外,在大型系列研究中并不明确。因此,本回顾性研究分析了 846 例至少 10 年随访的 TKA。

假设

多中心研究中 TKA 的 10 年生存率超过 90%,与设计和假体约束水平无关。

材料与方法

828 例患者(846 例 TKA)接受膝关节协会评分评估。平均年龄为 71 岁(范围,41-93 岁);274 例男性和 554 例女性(67%);496 例患者(60%)为活动型;主要诊断为骨关节炎(n=752[89%])。大多数 TKA 为骨水泥固定(n=704[83%]),髌骨置换(n=668[79%]),后十字韧带(PCL)切除(n=707[84%]),65%为后稳定型,35%为超关节型,固定(39%)或活动(61%)轴承。

结果

至少 10 年随访时,平均膝关节评分从 35 分(15-55 分)上升至 83 分(74-95 分),功能评分从 24 分(5-45 分)上升至 74 分(60-90 分);平均屈曲度从 105°(25-125°)上升至 112°(25-125°)。平均髋膝踝角为 179.5°(169-189°)。63 例(7.5%)需要进行翻修手术,主要原因是松动(n=18[2%])或感染(n=18[1.8%])。总体 10 年生存率为 92%(95%CI:0.90-0.94)。假体设计或 PCL 保留对生存率无显著影响。活动水平与翻修率相关;活动患者机械并发症更常见,而久坐患者感染并发症更常见。TKA 未在 177-183°范围内对线时,翻修并不更频繁。

讨论

10 年 TKA 生存率为 92%,与设计和机械应力水平无关。翻修主要是由于感染或松动,而不是由于 3°以上的轴对线不良。机械并发症在年轻和更活跃的患者中更为常见,因此应寻求其他治疗选择或技术改进。

证据水平

IV 级。回顾性研究。

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