Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Retina. 2013 Oct;33(9):1971-6. doi: 10.1097/IAE.0b013e3182923477.
To evaluate the choroidal thickness profiles of healthy children using enhanced depth imaging optical coherence tomography.
Horizontal and vertical enhanced depth imaging optical coherence tomography crosshair scans through the fovea were obtained from 48 healthy children. Choroidal thickness was measured at the fovea, 1 mm and 3 mm nasal, temporal, superior, and inferior to the fovea, and comparisons of choroidal thickness at different measurement points were performed.
The mean subfoveal choroidal thickness was 348.4 ± 82.5 μm and the thickness at 1 mm nasal, temporal, superior, and inferior to the fovea was 306.1 ± 86.3, 352.0 ± 84.8, 349.9 ± 83.8, and 343.8 ± 86.8 μm, respectively. The thickness at 3 mm nasal, temporal, superior, and inferior to the fovea was 190.1 ± 63.9, 339.2 ± 89.8, 330.7 ± 82.1, and 309.9 ± 78.4 μm, respectively. Subfoveal choroidal thickness was negatively correlated with age.
The data, obtained using enhanced depth imaging optical coherence tomography, provide the choroidal thickness profile of healthy children. The characteristic choroidal thickness profile in children suggests a redistribution process of choroidal tissue with aging.
利用增强深度成像光学相干断层扫描评估健康儿童的脉络膜厚度分布。
对 48 名健康儿童进行黄斑中心凹水平和垂直增强深度成像光学相干断层扫描十字线扫描。在黄斑中心凹、鼻侧 1mm、颞侧 1mm、上侧 1mm、下侧 1mm 处测量脉络膜厚度,并对不同测量点的脉络膜厚度进行比较。
平均黄斑中心凹下脉络膜厚度为 348.4 ± 82.5μm,鼻侧 1mm、颞侧 1mm、上侧 1mm、下侧 1mm 处的厚度分别为 306.1 ± 86.3μm、352.0 ± 84.8μm、349.9 ± 83.8μm、343.8 ± 86.8μm。鼻侧 3mm、颞侧 3mm、上侧 3mm、下侧 3mm 处的厚度分别为 190.1 ± 63.9μm、339.2 ± 89.8μm、330.7 ± 82.1μm、309.9 ± 78.4μm。黄斑中心凹下脉络膜厚度与年龄呈负相关。
本研究利用增强深度成像光学相干断层扫描获得了健康儿童的脉络膜厚度数据,为儿童脉络膜厚度分布提供了参考。儿童特有的脉络膜厚度分布特征提示脉络膜组织随年龄增长发生再分布过程。