Yan M
Shanghai Jin-An District Central Hospital.
Zhong Xi Yi Jie He Za Zhi. 1990 Feb;10(2):88-9, 69.
The patients with congestive heart failure which were treated by combination of digoxin with cyclovirobuxine D were described, with good result, of which prominating effect was 45.5%. Researchful result of 11 patients showed serum concentration of digoxin before and after combined treatment was not obviously different (P less than 0.05). Basis of pharmacokinetics was provided for using combined treatment of these drugs with long time and greater safeness.
描述了地高辛与环维黄杨星D联合治疗充血性心力衰竭患者的情况,效果良好,显效为45.5%。11例患者的研究结果显示联合治疗前后地高辛血清浓度无明显差异(P<0.05)。为长期联合应用这些药物提供了药代动力学依据,且安全性更高。