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[肺泡型和囊型棘球蚴病患者血清免疫球蛋白水平的比较]

[Comparison of serum immunoglobulin levels in patients with alveolar and cystic echinococcosis].

作者信息

Zhang J, Liu B, Li Y, Wang H, Zhu K, Sun Z, Liu J, Li M

机构信息

Department of Parasitology Ningxia Medical College.

出版信息

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1990;8(1):38-40.

PMID:2364503
Abstract

Serum IgG, IgA and IgM levels of 91 patients with alveolar echinococcosis and 83 patients with cystic echinococcosis were compared with 104 healthy adults as controls by single radial immunodiffusion. The mean IgG, IgA and IgM concentrations in patients with alveolar echinococcosis and the mean IgG and IgM levels in patients with cystic echinococcosis were found to be significantly higher than those of the normal controls. The mean IgG, IgA and IgM levels in patients with alveococcosis were 510 +/- 413.06, 389.45 +/- 433.42 and 313.48 +/- 255.19, while those in cystococcosis were 308.36 +/- 339.24, 329.61 +/- 319 and 266.68 +/- 255.68 respectively. The geometric mean of IgG and IgM levels in patients with alveococcosis was 1.67 and 1.25 times that in cystococcosis. 76.9% of alveococcosis patients had IgG levels reaching 200 IU/ml or above, being significantly higher than that in the cystic hydatidosis (50.6%). 93.4% of alveolar echinococcosis cases showed elevated IgM levels up to 100 IU/ml or more, being also significantly higher than that of cystic echinococcosis cases (78.3). Statistically, there was significant correlation between IgG concentration and ELISA antibody titre.

摘要

采用单向免疫扩散法,将91例肺泡型包虫病患者和83例囊型包虫病患者的血清IgG、IgA和IgM水平与104名健康成年人作为对照进行比较。发现肺泡型包虫病患者的平均IgG、IgA和IgM浓度以及囊型包虫病患者的平均IgG和IgM水平显著高于正常对照组。肺泡型包虫病患者的平均IgG、IgA和IgM水平分别为510±413.06、389.45±433.42和313.48±255.19,而囊型包虫病患者的分别为308.36±339.24、329.61±319和266.68±255.68。肺泡型包虫病患者IgG和IgM水平的几何平均值分别是囊型包虫病患者的1.67倍和1.25倍。76.9%的肺泡型包虫病患者IgG水平达到200 IU/ml或以上,显著高于囊型包虫病患者(50.6%)。93.4%的肺泡型包虫病病例IgM水平升高至100 IU/ml或更高,也显著高于囊型包虫病病例(78.3%)。统计学分析显示,IgG浓度与ELISA抗体滴度之间存在显著相关性。

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