Wright E P, Vlug A, Geertzen H G, Hoang T L, Nguyen D H
Int J Lepr Other Mycobact Dis. 1985 Jun;53(2):225-32.
Levels of serum immunoglobulins were measured in healthy Vietnamese and in leprosy patients. Healthy Vietnamese had higher levels of IgG, IgA, IgM, and IgE than did healthy Dutch controls, as well as higher levels of three of the four subclasses of IgG (IgG1, IgG2, IgG3). Lepromatous leprosy patients had significant increases in all classes and subclasses of immunoglobulins, except for IgG2, in comparison with local controls. Tuberculoid leprosy patients had more IgG1, IgG3, and IgG4 than did local controls and had higher total IgG levels. The patients had no increase in autoantibodies against tissue antigens compared to local or Dutch controls.
对健康越南人和麻风病患者的血清免疫球蛋白水平进行了测量。健康越南人的IgG、IgA、IgM和IgE水平高于健康荷兰对照，IgG的四个亚类中的三个亚类（IgG1、IgG2、IgG3）水平也更高。与当地对照相比，瘤型麻风病患者除IgG2外，所有免疫球蛋白类别和亚类均显著增加。结核样型麻风病患者的IgG1、IgG3和IgG4比当地对照更多，总IgG水平也更高。与当地或荷兰对照相比，这些患者针对组织抗原的自身抗体没有增加。
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