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肝素在主动脉夹层中的应用:谨防急性肺栓塞的误诊。

Use of heparin in aortic dissection: beware the misdiagnosis of acute pulmonary embolism.

作者信息

Sinha Yashashwi, Saleh Mahdi, Weinberg Daniel

机构信息

Keele University Medical School, Stoke-on-Trent, UK.

出版信息

BMJ Case Rep. 2013 May 2;2013:bcr2013009367. doi: 10.1136/bcr-2013-009367.

Abstract

We present a case which highlights the diagnostic difficulties between a Stanford type A aortic dissection (AD) and a pulmonary embolism (PE) and the impact it has on subsequent management. A 75-year-old man presenting with chest pain, shortness of breath and dizziness was initially suspected of having a PE and started on low-molecular-weight-heparin (LMWH). The patient was correctly diagnosed afterwards with CT of the chest to have an aortic dissection. The detrimental use of LMWH may have caused a propagation of the dissection and delayed surgical intervention of an acutely life-threatening condition. When the diagnosis is unclear, the early use of CT can help differentiate AD from PE. This in-turn can guide the management as well as the use of LMWH, which should be avoided until the correct diagnosis is confirmed.

摘要

我们报告一例病例,该病例凸显了斯坦福A型主动脉夹层(AD)与肺栓塞(PE)之间的诊断困难及其对后续治疗的影响。一名75岁男性,出现胸痛、气短和头晕,最初怀疑患有PE,并开始使用低分子肝素(LMWH)。随后通过胸部CT正确诊断为主动脉夹层。LMWH的不当使用可能导致夹层扩展,并延误了对急性危及生命状况的手术干预。当诊断不明确时,早期使用CT有助于鉴别AD和PE。这进而可以指导治疗以及LMWH的使用,在确诊之前应避免使用LMWH。

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