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硬皮病患者中酷似脑肿瘤的颅内肉芽肿。

Intracranial granuloma mimicking a brain tumor in a patient with scleroderma.

作者信息

Patel Amit, Rathi Nitika, Lee Maggie K, Baborie Atik, Jenkinson Michael D

机构信息

Department of Neurosurgery, Walton Centre for Neurology and Neurosurgery, Lower Lane, L9 7LJ, UK.

出版信息

Surg Neurol Int. 2013 Apr 18;4:54. doi: 10.4103/2152-7806.110651. Print 2013.

Abstract

BACKGROUND

Intracranial granulomatous masses presenting as space occupying lesions, although rare, have been described in the literature. Causes include infections, systemic granulomatous disorders, and iatrogenic from previous surgery. We present a case demonstrating that spontaneous intracranial granuloma can exist, often mimicking a brain tumor.

CASE DESCRIPTION

A 62-year-old female presented with a short history of left sided partial seizures and a left hemiparesis. Magnetic resonance imaging revealed a right sided parafalcine lesion. Histopathology demonstrated chronic inflammation of granulomatous type. She responded to steroid treatment.

CONCLUSION

She responded to steroid treatment. Our case demonstrated that spontaneous intracranial granuloma exists. Although rare, it should be considered in patients presenting with space occupying lesions. They can successfully be managed with steroid treatment.

摘要

背景

颅内肉芽肿性肿块表现为占位性病变,虽较为罕见,但文献中已有描述。病因包括感染、系统性肉芽肿性疾病以及既往手术导致的医源性因素。我们报告一例病例,表明自发性颅内肉芽肿可以存在,且常酷似脑肿瘤。

病例描述

一名62岁女性,有左侧部分性癫痫发作和左侧偏瘫的短暂病史。磁共振成像显示右侧大脑镰旁病变。组织病理学显示为肉芽肿型慢性炎症。她对类固醇治疗有反应。

结论

她对类固醇治疗有反应。我们的病例表明自发性颅内肉芽肿是存在的。尽管罕见,但对于出现占位性病变的患者应予以考虑。它们可以通过类固醇治疗成功处理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9a8/3640227/56778a2458d2/SNI-4-54-g001.jpg

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