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[骨髓移植后慢性移植物抗宿主病中的同种异体皮肤移植]

[Allogeneic skin transplantation in chronic graft-versus-host disease following bone marrow transplantation].

作者信息

Baumeister R G, Riel K A, Kolb H J

机构信息

Chirurgische Klinik und Poliklinik, Klinikum Grosshadern, Ludwig-Maximilians-Universität München.

出版信息

Chirurg. 1990 Jun;61(6):438-40.

PMID:2364784
Abstract

A 20-year old patient with acute myelogenous leukemia was transplanted with allogeneic bone marrow transplantation from his HLA-identical brother. Chronic graft-versus-host disease with ulcerous skin lesions developed at both lower legs. The lesions were extensive and conservative therapy was unsuccessful. Therefore, allogeneic skin transplantation from the marrow donor was performed. At present, four years later, these skin grafts are still vital.

摘要

一名20岁的急性髓性白血病患者接受了来自其 HLA 配型相同的哥哥的异基因骨髓移植。患者双下肢出现了伴有溃疡性皮肤病变的慢性移植物抗宿主病。病变范围广泛,保守治疗未成功。因此,进行了来自骨髓供体的异基因皮肤移植。目前,四年过去了,这些皮肤移植片仍然存活。

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