Kondo S, Tamura K, Makino S, Takamatsu Y
Blood Transfusion Division, Miyazaki Medical College, Japan.
Int J Hematol. 1994 Aug;60(2):151-5.
A 35-year-old female with chronic myelogenous leukemia in chronic phase underwent allogeneic bone marrow transplantation from her genotypically-matched brother in 1990. The extensive chronic graft-versus-host skin disease supervened with skin ulcers on both lower legs in 1992. Conservative therapy was unsuccessful for these lesions. Therefore, not only autologous skin grafting but also allogeneic skin grafting from the marrow donor was successfully performed. She has been maintaining her daily activities (Karnofsky performance status 90%) with little limitation for 17 months after the final skin grafting.
一名35岁处于慢性期的慢性粒细胞白血病女性患者于1990年接受了来自其基因匹配的兄弟的异基因骨髓移植。1992年出现了广泛的慢性移植物抗宿主皮肤病，双下肢出现皮肤溃疡。针对这些病变的保守治疗未成功。因此，不仅成功进行了自体皮肤移植，还成功进行了来自骨髓供体的异体皮肤移植。在最后一次皮肤移植后17个月来，她一直能维持日常活动（卡诺夫斯基功能状态90%），几乎没有限制。
