Gao S Z
First Affiliated Hospital of Hubei Medical College, Wuhan.
Zhonghua Wai Ke Za Zhi. 1990 Jan;28(1):13-5, 60.
Myocardial hypothermia during extracorporeal circulation is commonly created by perfusion of cool cardioplegic solution into the ascending aorta and burial of ice sludge in the pericardial sac. Measurement of temperature of the atrial and ventricular septums during animal experiment and operations for ASD and VSD showed: (1) The temperature was obviously higher in the atrial septum than ventricular. (2) The atrial and ventricular temperature exceeded 15 degrees C 5 minutes after cardioplegic perfusion. (3) Influence on postoperative heart rate and rhythm was obvious when ventricular temperature raised above 15 degrees C during cardiac arrest, especially when the temperature difference between the atrium and ventricule was above 3 degrees C. But this influence may be decreased by maintaining ventricular temperature below 15 degrees C and temperature gradient less than 3 degrees C with a combination of cardioplegic perfusion, ice sludge in pericardial sac plus constant lavage of intracardiac cavity with saline at 4 degrees C.
体外循环期间的心肌低温通常是通过向升主动脉灌注冷心脏停搏液以及在心包腔内埋入冰泥来实现的。在动物实验以及房间隔缺损和室间隔缺损手术中对房间隔和室间隔温度的测量显示:(1)房间隔温度明显高于心室温度。(2)心脏停搏液灌注5分钟后,心房和心室温度超过15摄氏度。(3)心脏停搏期间,当心室温度升至15摄氏度以上时,对术后心率和节律有明显影响,尤其是当心房和心室之间的温差超过3摄氏度时。但是,通过心脏停搏液灌注、心包腔内冰泥加上用4摄氏度生理盐水持续灌洗心腔,将心室温度维持在15摄氏度以下且温度梯度小于3摄氏度,这种影响可能会降低。