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[迷走神经切断术后胃壁的组织化学和电子显微镜观察]

[Histochemical and electron microscopic observation of the gastric wall after vagotomy].

作者信息

Chen D D

机构信息

Union Hospital, Tongji Medical University, Wuhan.

出版信息

Zhonghua Wai Ke Za Zhi. 1990 Feb;28(2):110-2, 128.

PMID:2364823
Abstract

Eight dogs underwent gastric total truncal vagotomy and another 8 had gastric superselective vagotomy. Specimens were take from anterior wall of gastric corpus and antrum at weeks after operation for histochemical and electron microscopic observation. The results showed: (1) the sympathetic postganglionic fibers in gastric wall were completely damaged. (2) response of gastric antrum mucosa to CCK-8 and gastric G-17 lowered markedly. (3) the amount of parietal cells increased, the structure of follicular atrophied, the number of mitochondrion in cytoplasm, and the stroma and micrailli on folilculi wall increased. (4) The Campylobacter-like organism (CLO) were found in mucosa of gastric antrum and corpus after operation. The authors discussed the role of gastric sympathetic nerve on gastric secretion and movement, and the relationship between CLO and ulcer recurrence after gastric superselective vagotomy.

摘要

8只狗接受了胃全迷走神经干切断术,另外8只接受了胃超选择性迷走神经切断术。术后数周从胃体和胃窦前壁取标本进行组织化学和电子显微镜观察。结果显示:(1)胃壁交感神经节后纤维完全受损。(2)胃窦黏膜对CCK - 8和胃泌素G - 17的反应明显降低。(3)壁细胞数量增加,滤泡结构萎缩,细胞质中线粒体数量以及滤泡壁上的基质和微绒毛增加。(4)术后在胃窦和胃体黏膜中发现了类弯曲杆菌(CLO)。作者讨论了胃交感神经对胃分泌和运动的作用,以及胃超选择性迷走神经切断术后CLO与溃疡复发之间的关系。

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