Fang Xi-ye, Liu Qi-yong, Xu Lei, Zhou Dong-sheng, Cui Yu-jun, Dong Xing-qi, Zhang Rong-zu, Gu Shao-hua, Ye Cai-de, Yang Rui-fu
Institute of Laboratory Animal Sciences of Chinese Academy of Medical Sciences, Beijing, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2013 Jan;34(1):91-7.
Since plague is an important natural focus zoonosis, the typing of natural plague foci becomes one of the elements in understanding the nature and developing related prevention program of the disease. Natural foci of plague are composed by four fundamental parts which include Eco-geographical landscape (natural plague foci), hosts, vectors and pathogens (Yersinia pestis) that comprehensively interact through the large temporal scale of evolution. Human activities have had great impact on the foci of natural plague. Based on the published serial research papers, we tried to integrate the knowledge of each factor in natural plague foci and focusing on theoretical aspects, so as to strengthen the prevention and surveillance programs of plague to be extrapolated to other zoonosis.
由于鼠疫是一种重要的自然疫源性人畜共患病,自然鼠疫疫源地的分型成为了解该疾病本质和制定相关预防计划的要素之一。鼠疫自然疫源地由四个基本部分组成,包括生态地理景观(自然鼠疫疫源地)、宿主、媒介和病原体(鼠疫耶尔森菌),它们在漫长的进化时间尺度上相互作用。人类活动对自然鼠疫疫源地产生了重大影响。基于已发表的系列研究论文,我们试图整合自然鼠疫疫源地各因素的知识,并聚焦于理论层面,以加强鼠疫的预防和监测计划,并推广到其他人畜共患病。