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成瘾的药物治疗

Pharmacotherapies of addiction.

作者信息

Qureshi Naseem A, Al-Habeeb Tariq A, Al-Ghamdy Yaseer S

机构信息

Buraidah Mental Health Hospital, PO Box 2292, Buraidah, Kingdom of Saudi Arabia. Tel. +966 (6) 3852242. Fax. +966 (6) 3853010. E-mail:

出版信息

Neurosciences (Riyadh). 2003 Jan;8(1):34-42.

PMID:23648984
Abstract

OBJECTIVE

Millions of drug addicts worldwide require proper treatment together with good quality care. This article aims to critically review the psychopharmacology of drug addictions.

METHODS

MEDLINE was systematically searched for studies describing drug treatment of addictions. Numerous studies were obtained and grouped according to the drug used to treat addictions.

RESULTS

Although there are many effective antiaddictive drugs in the therapeutic armamentarium of drug addictions, a great number of patients tend to develop poor drug compliance, multiple relapses, and continue to suffer from chronic addictions coupled with negative biopsychosocial consequences.

CONCLUSION

Aside from enhancing the public awareness of the devastating effects of drug addictions through regular and effective mass media campaigns, scientific efforts should be continued in order to develop new antiaddictive drugs with better clinical profiles for the treatment of patients with addictions.

摘要

目的

全球数百万吸毒成瘾者需要得到妥善治疗以及高质量护理。本文旨在对药物成瘾的精神药理学进行批判性综述。

方法

系统检索MEDLINE数据库,查找描述药物成瘾治疗的研究。获取了大量研究,并根据用于治疗成瘾的药物进行分组。

结果

尽管在药物成瘾的治疗手段中有许多有效的抗成瘾药物,但大量患者往往出现药物依从性差、多次复发的情况,并继续遭受慢性成瘾问题以及负面的生物心理社会后果。

结论

除了通过定期且有效的大众媒体宣传活动提高公众对药物成瘾破坏性影响的认识外,还应继续开展科学研究,以开发具有更好临床特征的新型抗成瘾药物,用于治疗成瘾患者。

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