催产素可刺激老龄雄性大鼠的性行为。

Sexual behavior of aging male rats is stimulated by oxytocin.

作者信息

Arletti R, Benelli A, Bertolini A

机构信息

Institute of Pharmacology, University of Modena, Italy.

出版信息

Eur J Pharmacol. 1990 Apr 25;179(3):377-81. doi: 10.1016/0014-2999(90)90178-9.

DOI:10.1016/0014-2999(90)90178-9

PMID:2364993

Abstract

The effect of oxytocin on male sexual behavior was investigated in sexually normal or sexually sluggish 20-month-old rats. Rats were tested seven times, at weekly intervals, for copulatory behavior in the presence of receptive females. Oxytocin (0.1 microgram), injected intraperitoneally 60 min before the eighth test, significantly shortened the mount, intromission and ejaculation latencies and post-ejaculation intervals, the effect being proportionately greater in the sexually sluggish rats. These data confirm that oxytocin plays a facilitatory role in mating behavior and suggest that it may prove useful in conditions of copulatory inadequacy.

摘要

研究了催产素对性正常或性迟缓的20月龄大鼠雄性性行为的影响。每周对大鼠进行一次测试，共测试七次，观察其在有接受交配雌鼠存在时的交配行为。在第八次测试前60分钟腹腔注射催产素（0.1微克），显著缩短了爬跨、插入和射精潜伏期以及射精后间隔时间，在性迟缓的大鼠中这种作用更为明显。这些数据证实催产素在交配行为中起促进作用，并表明它在交配功能不全的情况下可能有用。