Department of Anesthesiology and Pain Medicine, Seattle, WA 98105, USA.
Pediatrics. 2013 Jun;131(6):e1850-6. doi: 10.1542/peds.2012-3354. Epub 2013 May 6.
To compare the extent of disability in multiple areas of functioning after mild, moderate, and severe traumatic brain injury (TBI) between Hispanic and non-Hispanic white (NHW) children.
This was a prospective cohort study of children aged <18 years treated for a TBI between March 1, 2007, and September 30, 2008. Hispanic (n = 74) and NHW (n = 457) children were included in the study. Outcome measures were disability in health-related quality of life, adaptive skills, and participation in activities 3, 12, 24, and 36 months after injury compared with preinjury functioning. We compared change in outcome scores between Hispanic and NHW children at each follow-up time. All analyses were adjusted for age, gender, severity and intent of injury, insurance, family function at baseline, parental education, and income.
The health-related quality of life for all children was lower at all follow-up times compared with baseline. Although NHW children showed some improvement during the first 3 years after injury, Hispanic children remained significantly impaired. Significant differences were also observed in the domains of communication and self-care abilities after TBI. Differences between groups in scores for participation in activities were also present but were only significant 3 months after injury.
Hispanic children with TBI report larger and long-term reductions in their quality of life, participation in activities, communication, and self-care abilities compared with NHW children. The reasons for these differences need to be better understood and interventions implemented to improve the outcomes of these children.
比较轻度、中度和重度创伤性脑损伤(TBI)后 Hispanic 和非 Hispanic 白种人(NHW)儿童多个功能领域残疾的程度。
这是一项对 2007 年 3 月 1 日至 2008 年 9 月 30 日期间因 TBI 接受治疗的 <18 岁儿童进行的前瞻性队列研究。研究纳入了 Hispanic(n = 74)和 NHW(n = 457)儿童。主要结局为损伤后 3、12、24 和 36 个月与损伤前相比,健康相关生活质量、适应性技能和活动参与度的残疾程度。我们比较了每个随访时间 Hispanic 和 NHW 儿童之间结局评分的变化。所有分析均调整了年龄、性别、损伤严重程度和损伤意图、保险、基线家庭功能、父母教育程度和收入。
与基线相比,所有儿童在所有随访时间的健康相关生活质量均较低。尽管 NHW 儿童在损伤后前 3 年有所改善,但 Hispanic 儿童仍明显受损。在 TBI 后,沟通和自理能力方面也存在显著差异。在活动参与度方面,组间评分差异也存在,但仅在损伤后 3 个月时具有统计学意义。
与 NHW 儿童相比,患有 TBI 的 Hispanic 儿童报告生活质量、活动参与度、沟通和自理能力的降低幅度更大且持续时间更长。需要更好地了解这些差异的原因,并实施干预措施以改善这些儿童的结局。