Key Laboratory of Coastal Biology and Bioresource Utilization, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences , Yantai 264003, China.
Org Lett. 2013 May 17;15(10):2327-9. doi: 10.1021/ol4009624. Epub 2013 May 7.
A novel carbamate- and cyano-containing alkaloid, aspeverin (1), was isolated from the culture of an algicolous Aspergillus versicolor strain (dl-29). The structure and absolute configuration were unambiguously identified by NMR, IR, ECD, and mass spectrometric methods as well as quantum chemical calculations. 1 exhibited potent bioactivities against some marine-derived organisms.
从一株海洋来源的青霉（dl-29）的发酵液中分离得到了一个新型的含氨基甲酸酯和氰基的生物碱，asperverin（1）。通过 NMR、IR、ECD 和质谱等方法以及量子化学计算，明确鉴定了其结构和绝对构型。化合物 1 对一些海洋来源的生物表现出很强的生物活性。
