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皮肤结节病与英夫利昔单抗:难治性疾病疗效证据

Cutaneous sarcoidosis and infliximab: evidence for efficacy in refractory disease.

作者信息

Tu Jenny, Chan Jonathan

机构信息

Department of Dermatology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.

出版信息

Australas J Dermatol. 2014 Nov;55(4):279-81. doi: 10.1111/ajd.12056. Epub 2013 May 8.

Abstract

Biological therapy with tumour necrosis factor alpha antibodies continues to offer a life-changing option for a range of autoimmune and inflammatory skin conditions. We present three cases of sarcoidosis, with refractory cutaneous disease successfully treated with infliximab. A review of the literature shows increased numbers of cases of refractory cutaneous sarcoidosis successfully cleared with infliximab therapy.

摘要

使用肿瘤坏死因子α抗体的生物疗法继续为一系列自身免疫性和炎症性皮肤病提供改变生活的选择。我们报告三例结节病患者,其难治性皮肤疾病通过英夫利昔单抗成功治疗。文献综述显示,英夫利昔单抗治疗成功清除难治性皮肤结节病的病例数量有所增加。

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