Amtage Florian, Lambeck Johann, Rutsch Sebastian, Prokop Thomas, Pinsker Marcus, Rijntjes Michel
Department of Neurology, University Medical Center Freiburg, Breisacherstr. 64, Freiburg, 79106, Germany,
Acta Neurochir Suppl. 2013;117:43-6. doi: 10.1007/978-3-7091-1482-7_7.
Thalamotomy was formerly used to treat different tremor syndromes. Nowadays, deep brain stimulation has become an established technique to treat -different movement disorders. The combination of these two stereotactic interventions is rare.
We present a patient in which a right-sided tremor -syndrome with an underlying pathology of combined essential tremor and Parkinsonian tremor was successfully treated initially with a left-sided thalamotomy and subsequently with -bilateral deep brain stimulation in the subthalamic nucleus.
Deep brain stimulation in the subthalamic nucleus resulted in hemidystonia, pathological laughing and crying, dysarthria and dysphagia, all due to dislocation of the stimulation electrodes contacting the internal capsule. After discontinuation of the high-frequency stimulation these side-effects disappeared, but were then reactivated by an LCD television in stand-by mode.
In this report we discuss the pathophysiology of pseudobulbar symptoms and pathological laughing and crying in context of thalamotomy and dislocated DBS electrodes. Furthermore, we report on the occurrence that magnetic fields in the household have an impact on deep brain stimulation, even if they are in stand-by mode.
丘脑切开术曾用于治疗不同的震颤综合征。如今,脑深部电刺激已成为治疗不同运动障碍的成熟技术。这两种立体定向干预措施的联合应用较为罕见。
我们报告一例患者,其右侧震颤综合征合并特发性震颤和帕金森震颤的潜在病理改变,最初成功接受了左侧丘脑切开术治疗,随后接受了双侧丘脑底核脑深部电刺激治疗。
丘脑底核脑深部电刺激导致偏侧肌张力障碍、病理性哭笑、构音障碍和吞咽困难,均因刺激电极移位接触内囊所致。停止高频刺激后,这些副作用消失,但随后被处于待机模式的液晶电视重新激活。
在本报告中,我们结合丘脑切开术和移位的脑深部电刺激电极讨论了假性球麻痹症状及病理性哭笑的病理生理学。此外,我们报告了即使处于待机模式,家庭中的磁场也会对脑深部电刺激产生影响的情况。