Rethorst Chad D, Trivedi Madhukar H
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390-9119, USA.
J Psychiatr Pract. 2013 May;19(3):204-12. doi: 10.1097/01.pra.0000430504.16952.3e.
Major depressive disorder (MDD) is a source of great disease burden, due in part to the limited accessibility and effectiveness of current treatments. Although current treatments are efficacious in a segment of the population with MDD, there is a clear need for alternative and augmentation treatment strategies. Exercise is one such alternative treatment option. Research has shown exercise to be efficacious as both a stand-alone and an augmentation therapy. As a result, exercise is now included in the American Psychiatric Association's treatment recommendations. The purpose of this article is to provide clinicians with a knowledge base to prescribe exercise to their patients. The authors describe the evidence supporting the use of exercise in the treatment of MDD, provide evidence-based recommendations for prescribing exercise, and address practical considerations related to prescribing exercise in real-world treatment settings.
重度抑郁症（MDD）是巨大疾病负担的一个来源，部分原因在于当前治疗方法的可及性和有效性有限。尽管当前治疗方法对一部分患有MDD的人群有效，但显然需要替代和强化治疗策略。运动就是这样一种替代治疗选择。研究表明，运动作为一种独立治疗方法和强化治疗方法均有效。因此，运动现已被纳入美国精神病学协会的治疗建议中。本文的目的是为临床医生提供一个知识基础，以便他们为患者开具运动处方。作者描述了支持运动用于治疗MDD的证据，提供了基于证据的运动处方建议，并阐述了在实际治疗环境中开具运动处方的实际考量。
