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[与接触致敏相关的多形红斑。6例临床病例描述]

[Erythema multiforme associated with contact sensitization. Description of 6 clinical cases].

作者信息

Seidenari S, Di Nardo A, Motolese A, Pincelli C

机构信息

Università di Modena, Clinica Dermatologica.

出版信息

G Ital Dermatol Venereol. 1990 Feb;125(1-2):35-40.

PMID:2365402
Abstract

Allergic contact dermatitis generally presents itself as an eczematous eruption. However, some allergens, such as plants, exotic woods, topical medications and chemicals have been reported as causing an erythema multiforme-like eruption. We describe 6 patients, 4 women and 2 men ranging from 28 to 66 years. They showed erythematous urticarial papules, plaques and target-lesions similar to the manifestations previously reported as "erythema multiforme-like eruption". On the basis of the positive epicutaneous tests, the aetiological agents of these reactions are presumed to be Idoxuridine, textile dyes, deodorants, paraphenylenediamine and pyrrolnitrin. The clinical pattern, the histopathological features and the pathogenesis are discussed. Finally, the clinical and anamnestic criteria indicating the opportunity of performing patch tests in patients showing an atypical erythema multiforme are suggested.

摘要

过敏性接触性皮炎通常表现为湿疹样皮疹。然而,一些过敏原,如植物、异国木材、外用药物和化学物质,已被报道可引起多形红斑样皮疹。我们描述了6例患者,4名女性和2名男性,年龄在28至66岁之间。他们表现出红斑性荨麻疹丘疹、斑块和靶形损害,类似于先前报道为“多形红斑样皮疹”的表现。基于皮试阳性,推测这些反应的病因是碘苷、纺织染料、除臭剂、对苯二胺和吡咯菌素。讨论了临床模式、组织病理学特征和发病机制。最后,提出了临床和既往史标准,以表明对表现为非典型多形红斑的患者进行斑贴试验的时机。

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