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大豆蛋白补充剂对超重和肥胖人群的影响:随机对照试验的荟萃分析

[Effects of soy protein supplement on overweight and obese population: meta-analysis of randomized controlled trials].

作者信息

Wu Jing, Dong Jiayi, Jiang Xia, Qin Liqiang

机构信息

Department of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou 215123, China.

出版信息

Wei Sheng Yan Jiu. 2013 Mar;42(2):185-9.

PMID:23654091
Abstract

OBJECTIVE

To study the effects of soy protein supplement on overweight and obese population.

METHODS

Randomized controlled trials (RCT) published from January 1988 to May 2012 observing the effect of soy protein supplement on overweight and obese population were collected. Meta-analysis was applied to estimate the standardized mean difference (WMD) and 95% confidence interval (95% CI).

RESULTS

Among 13 RCTs, the number of the studies observing change of body weight, body mass index (BMI), fat mass and waist circumference were 12, 7, 7 and 11, respectively. Compared with the control group, the combined WMD (95% CI) of soy protein supplemented was - 1.04 kg [( -1.97) - ( -0.11)], -0.19 kg/m2 [(-0.41) - (0.02)], -0.99 kg [(-1.73) - (-0.24)] and - 0.94 cm [(-1.66) - (-0.21)], respectively. However, the protective effect of soy protein was only observed among studies conducted in Western population, but not in Asian population.

CONCLUSION

Soy protein supplementation significantly decreased body weight, fat mass and waist circumference in overweight and obese population.

摘要

目的

研究补充大豆蛋白对超重和肥胖人群的影响。

方法

收集1988年1月至2012年5月发表的观察补充大豆蛋白对超重和肥胖人群影响的随机对照试验(RCT)。采用Meta分析来估计标准化均数差(WMD)和95%置信区间(95%CI)。

结果

在13项RCT中,观察体重、体重指数(BMI)、脂肪量和腰围变化的研究数量分别为12项、7项、7项和11项。与对照组相比,补充大豆蛋白的合并WMD(95%CI)分别为-1.04kg[(-1.97)-(-0.11)]、-0.19kg/m²[(-0.41)-(0.02)]、-0.99kg[(-1.73)-(-0.24)]和-0.94cm[(-1.66)-(-0.21)]。然而,大豆蛋白的保护作用仅在西方人群的研究中观察到,而在亚洲人群中未观察到。

结论

补充大豆蛋白可显著降低超重和肥胖人群的体重、脂肪量和腰围。

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