Department of Biosciences, University of Helsinki, Helsinki, Finland.
Mol Ecol Resour. 2013 Jul;13(4):746-54. doi: 10.1111/1755-0998.12111. Epub 2013 May 9.
Approaches and tools to differentiate between natural selection and genetic drift as causes of population differentiation are of frequent demand in evolutionary biology. Based on the approach of Ovaskainen et al. (2011), we have developed an R package (DRIFTSEL) that can be used to differentiate between stabilizing selection, diversifying selection and random genetic drift as causes of population differentiation in quantitative traits when neutral marker and quantitative genetic data are available. Apart from illustrating the use of this method and the interpretation of results using simulated data, we apply the package on data from three-spined sticklebacks (Gasterosteus aculeatus) to highlight its virtues. DRIFTSEL can also be used to perform usual quantitative genetic analyses in common-garden study designs.
区分自然选择和遗传漂变作为种群分化原因的方法和工具在进化生物学中经常被需要。基于 Ovaskainen 等人(2011)的方法,我们开发了一个 R 包(DRIFTSEL),当存在中性标记和数量遗传数据时,该包可用于区分数量性状中种群分化的稳定选择、多样化选择和随机遗传漂变的原因。除了使用模拟数据来说明这种方法的使用和结果的解释外,我们还将该软件包应用于三刺鱼(Gasterosteus aculeatus)的数据,以突出其优点。DRIFTSEL 还可以用于在常规花园研究设计中进行常用的数量遗传分析。