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金黄色苔藓:一种不寻常的组织病理学表现:病例报告及文献复习

Lichen aureus: an unusual histopathological presentation: a case report and a review of literature.

作者信息

Aung Phyu P, Burns Stacey J, Bhawan Jag

机构信息

*Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA; and †South Shore Skin Center, Plymouth, MA.

出版信息

Am J Dermatopathol. 2014 Jan;36(1):e1-4. doi: 10.1097/DAD.0b013e31828b4428.

Abstract

Lichen aureus (LA) presents an inflammatory infiltrate with a lichenoid pattern, which mainly localizes to the superficial dermis, and it is admixed with extravasated erythrocytes. We present the case of a 12-year-old male who had a 1.3-cm golden-brown-color patch on the right upper back for 2 weeks. Histopathologic examination revealed a lichenoid, superficial, and deep perivascular lymphocytic infiltrate with perineural and periappendageal involvement, extravasated erythrocytes, papillary dermal edema, and hemosiderophages. The perineural and periappendageal infiltrate is unusual for LA and suggestive of lichen striatus (LS). In addition, the presence of perineural inflammation is not a common feature for either LA or LS. However, given the clinical findings, taken together, these features were interpreted as being most consistent with LA. To the best of our knowledge, no previous case of LA has been reported with histological features of perineural inflammation and LS.

摘要

金黄色苔藓(LA)表现为具有苔藓样模式的炎症浸润,主要局限于浅表真皮,并混有外渗的红细胞。我们报告一例12岁男性病例,其右上背部有一个1.3厘米的金褐色斑块,持续2周。组织病理学检查显示为苔藓样、浅表和深部血管周围淋巴细胞浸润,伴有神经周围和附属器周围受累、外渗红细胞、乳头真皮水肿和含铁血黄素巨噬细胞。神经周围和附属器周围浸润在LA中不常见,提示线状苔藓(LS)。此外,神经周围炎症并非LA或LS的常见特征。然而,综合临床发现,这些特征被解释为最符合LA。据我们所知,以前没有LA病例报告具有神经周围炎症和LS的组织学特征。

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