Gaertner Erich, Elstein William
SaraPath Diagnostics, Sarasota, Florida, USA.
Dermatol Online J. 2012 Feb 15;18(2):11.
Lichen planus pigmentosus-inversus is a rare variant of lichen planus, with less than 20 cases reported in the medical literature. It presents as asymptomatic to mildly pruritic, hyperpigmented macules and/or patches involving intertriginous and flexural areas and skin folds in light-skinned individuals. The unique pattern of skin involvement, clinical features, and histology are distinctive. The combination of hyperpigmented lesion(s) isolated to non-sun exposed, intertriginous, and flexural areas with lichenoid histology is unique and separates it from other similar entities, such as lichen planus actinus and erythema dyschromicum perstans/ashy dermatosis. The case well highlights this unusual condition and represents the first case reported in the United States.
色素性扁平苔藓(反向型)是扁平苔藓的一种罕见变体,医学文献中报道的病例不到20例。在浅色皮肤个体中,它表现为无症状至轻度瘙痒的色素沉着斑和/或斑片,累及褶皱部位和皮肤皱褶处。其独特的皮肤受累模式、临床特征和组织学表现具有特异性。色素沉着病变孤立于非暴露于阳光的褶皱和弯曲部位,同时具有苔藓样组织学特征,这种组合是独特的,使其有别于其他类似疾病,如光化性扁平苔藓和持久性色素异常性红斑/灰泥样皮肤病。该病例很好地凸显了这种罕见病症,是美国报道的首例。