Department of Nursing, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Kochi, 783-8505, Japan.
J Gastroenterol. 2014 Apr;49(4):667-73. doi: 10.1007/s00535-013-0825-y. Epub 2013 May 9.
This study aimed to provide a psychometric evaluation of the Japanese version of the Patient Assessment of Constipation Quality of Life questionnaire (JPAC-QOL).
Data for scoring were collected prospectively from patients with constipation who visited our center from 2008 to 2010, and analyzed retrospectively. Reliability of the JPAC-QOL was evaluated using Cronbach's alpha to calculate internal consistency, and a test-retest study was performed to evaluate reproducibility. For concurrent validity assessment, the JPAC-QOL scores were compared with Constipation Scoring System (CSS) scores. In assessing responsiveness, the JPAC-QOL scores before and after treatments were compared in patients whose modified CSS (mCSS) scores decreased by >50 %.
Internal consistency was assessed in 295 patients (165 women; mean age 67.0 years). Cronbach's alpha was >0.7 for the overall score and all four subscales, showing a strong internal consistency. The intraclass correlations for the 145 patients available for the test-retest study were >0.7 for the overall score and for all subscales except satisfaction. The JPAC-QOL scores were significantly associated with the CSS scores in 284 patients, demonstrating concurrent validity in all four subscales and the overall score. The mean JPAC-QOL score improved significantly after treatment in the 72 patients whose mCSS scores decreased by >50 %, indicating good responsiveness in all four subscales and in the overall score.
Our study data confirmed the validity and reliability of the JPAC-QOL and demonstrated it ready for use in evaluating the symptom-specific QOL in Japanese patients with constipation.
本研究旨在对便秘患者生活质量问卷（JPAC-QOL）的日文版进行心理测量学评估。
从 2008 年至 2010 年，前瞻性地从我院就诊的便秘患者中收集评分数据，并进行回顾性分析。采用 Cronbach'α 评估 JPAC-QOL 的信度，以计算内部一致性，并进行重测研究以评估可重复性。为了评估同时效度，将 JPAC-QOL 评分与便秘评分系统（CSS）评分进行比较。在评估反应性方面，比较治疗前后改良 CSS（mCSS）评分降低>50%的患者的 JPAC-QOL 评分。
对 295 例患者（165 例女性；平均年龄 67.0 岁）进行了内部一致性评估。总体评分和四个亚量表的 Cronbach'α均>0.7，显示出较强的内部一致性。145 例可用于重测研究的患者的组内相关系数>0.7，除满意度外，所有亚量表的组内相关系数均>0.7。JPAC-QOL 评分与 284 例患者的 CSS 评分显著相关，在所有四个亚量表和总体评分中均具有同时效度。72 例 mCSS 评分降低>50%的患者治疗后 JPAC-QOL 评分显著改善，表明所有四个亚量表和总体评分均具有良好的反应性。
本研究数据证实了 JPAC-QOL 的有效性和可靠性，表明它可用于评估日本便秘患者的症状特异性生活质量。
