Owens W E, Watts J L, Greene B B, Ray C H
Hill Farm Research Station, Louisiana Agricultural Experiment Station, Louisiana State University Agricultural Center, Homer 71040.
J Dairy Sci. 1990 May;73(5):1225-31. doi: 10.3168/jds.S0022-0302(90)78786-3.
The antimicrobial susceptibility to 11 antibiotics was determined of 358 streptococcal isolates representing six species was determined. All isolates were from milk samples obtained from clinical or subclinical cases of bovine mastitis. Agar disk diffusion zone diameters and minimum inhibitory concentrations were obtained for all isolates. Of the antibiotics tested that are available for mastitis therapy, cephalothin, penicillin, ampicillin, novobiocin, and erythromycin demonstrated acceptable activity against nonenterococcal streptococci, but only penicillin and ampicillin demonstrated moderate activity against Enterococcus faecalis. Enterococcus faecalis demonstrated substantial resistance to cephalothin, erythromycin, gentamicin, streptomycin, and tetracycline, while the nonenterococcal streptococci demonstrated substantial resistance to gentamicin, streptomycin, and tetracycline. Streptococcus uberis demonstrated greater antibiotic resistance than did Streptococcus dysgalactiae, while Aerococcus viridans demonstrated the greatest overall resistance of the nonenterococcal species.
对代表六种链球菌的358株链球菌分离株进行了11种抗生素的药敏试验。所有分离株均来自临床或亚临床型牛乳腺炎病例的牛奶样本。测定了所有分离株的琼脂扩散盘直径和最低抑菌浓度。在用于乳腺炎治疗的受试抗生素中，头孢噻吩、青霉素、氨苄青霉素、新生霉素和红霉素对非肠球菌性链球菌表现出可接受的活性，但只有青霉素和氨苄青霉素对粪肠球菌表现出中度活性。粪肠球菌对头孢噻吩、红霉素、庆大霉素、链霉素和四环素表现出高度耐药性，而非肠球菌性链球菌对庆大霉素、链霉素和四环素表现出高度耐药性。乳房链球菌比停乳链球菌表现出更高的抗生素耐药性，而绿色气球菌在非肠球菌性菌种中表现出总体最高的耐药性。
