Matthews K A, Wing R R, Kuller L H, Meilahn E N, Kelsey S F, Costello E J, Caggiula A W
Department of Psychiatry, University of Pittsburgh, Pennsylvania 15213.
J Consult Clin Psychol. 1990 Jun;58(3):345-51. doi: 10.1037//0022-006x.58.3.345.
We investigated the psychological and symptom consequences of the natural menopause in a longitudinal study of 541 initially premenopausal healthy women. All women were given an extensive evaluation at baseline. After 3 years of follow-up, 69 women ceased cycling for 12 months; another 32 women had ceased cycling and had taken hormone replacement therapy for a total of 12 months. These women were reevaluated in a clinic examination identical with the baseline examination, as were 101 age-matched premenopausal control women. Comparison among groups at the baseline and follow-up examination showed that natural menopause led to few changes in psychological characteristics, with only a decline in introspectiveness and an increase in reports of hot flashes being apparent. We conclude that natural menopause did not have negative mental health consequences for the majority of middle-aged healthy women.
我们在一项对541名最初处于绝经前期的健康女性进行的纵向研究中，调查了自然绝经的心理及症状后果。所有女性在基线时均接受了全面评估。经过3年的随访，69名女性停经12个月；另有32名女性已停经且接受了总共12个月的激素替代疗法。这些女性在与基线检查相同的门诊检查中接受了重新评估，101名年龄匹配的绝经前对照女性也接受了同样的检查。基线检查和随访检查时的组间比较显示，自然绝经导致心理特征变化很少，仅内省性有所下降，潮热报告有所增加。我们得出结论，自然绝经对大多数中年健康女性没有负面心理健康影响。
