Gorbachevskaya A I
I.P. Pavlov Institute of Physiology, St. Petersburg, Russia
Morfologiia. 2012;142(6):10-4.
The method of retrograde axonal transport of horseradish peroxidase was used to study the organization of the projections of the morpho-functional system of the basal ganglia nuclei to the individual substructures of the of deep mesencephalic nucleus complex (DMNC) of dog brain (n = 9). It was found that the nucleus accumbens was the only striatum structure containing the neurons that sent projection fibers to the subcuneate nucleus. The projections of the output structures of the basal ganglia--pallidum, substantia nigra, zona incerta, pedunculopontine nucleus were more numerous in DMNC. It was demonstrated that not all DMNC substructures received projection fibers from the neurons of all the nuclei of the basal ganglia structures mentioned. Thus, the fibers from the neurons of the globus pallidus and the ventral pallidum innervated the cuneiform and the subcuneiform nuclei, while those from the entopeduncular nucleus projected to all the DMNC substructures. The projection fibers from the zona incerta neurons were directed to the subcuneate nucleus and to the deep mesencephalic nucleus, while those from the pedunculopontine nucleus projected to the cuneate and the subcuneate nuclei. The projections from the substantia nigra neurons were directed to all the substructures of DMNC.
采用辣根过氧化物酶逆行轴突运输法，研究犬脑（n = 9）基底神经节核形态功能系统向中脑深核复合体（DMNC）各亚结构的投射组织。发现伏隔核是纹状体中唯一含有向楔下核发送投射纤维的神经元的结构。基底神经节输出结构——苍白球、黑质、未定带、脚桥核在DMNC中的投射较多。结果表明，并非DMNC的所有亚结构都接受上述基底神经节结构所有核的神经元发出的投射纤维。因此，苍白球和腹侧苍白球神经元的纤维支配楔状核和楔下核，而内苍白球核的纤维投射到DMNC的所有亚结构。未定带神经元的投射纤维指向楔下核和中脑深核，而脚桥核的纤维投射到楔状核和楔下核。黑质神经元的投射指向DMNC的所有亚结构。
