Pascual M, Sánchez-González B, García M, Pera M, Grande L
Rev Esp Enferm Dig. 2013 Feb;105(2):74-8. doi: 10.4321/s1130-01082013000200003.
primary colorectal lymphoma is a very rare disease, representing less than 0.5 % of all primary colorectal neoplasms. The gastrointestinal tract is the most frequently involved site of all extranodal lymphomas, the most common type of that is non-Hodgkin s lymphoma. Early diagnosis is often difficult because of unspecific symptoms. Therapeutic approaches have classically included radical resection, chemotherapy and radiotherapy.
we present our experience in the management of primary colorectal lymphomas over a 17-year period (1994-20011).
in this period 7 cases of primary colorectal lymphoma were diagnosed in our institution. Abdominal pain and change in bowel habit were the most frequent symptoms. Five patients underwent emergency surgery because of bleeding or bowel obstruction. All primary intestinal lymphomas studied were of the Bcell phenotype. Patients were followed up for a median of 59 months (range 1-180). Three of them are alive with no evidence of recurrence.
combination treatment with chemotherapy and surgery can obtain good remission rate. Surgery can resolve complications such bleeding or intestinal perforation that are implicated in lymphoma mortality.
原发性结直肠淋巴瘤是一种非常罕见的疾病，占所有原发性结直肠肿瘤的比例不到0.5%。胃肠道是所有结外淋巴瘤最常累及的部位，其中最常见的类型是非霍奇金淋巴瘤。由于症状不具特异性，早期诊断往往困难。传统的治疗方法包括根治性切除、化疗和放疗。
我们介绍了17年期间（1994 - 2011年）原发性结直肠淋巴瘤的治疗经验。
在此期间，我们机构诊断出7例原发性结直肠淋巴瘤。腹痛和排便习惯改变是最常见的症状。5例患者因出血或肠梗阻接受了急诊手术。所有研究的原发性肠道淋巴瘤均为B细胞表型。患者的中位随访时间为59个月（范围1 - 180个月）。其中3例存活且无复发迹象。
化疗与手术联合治疗可获得良好的缓解率。手术可解决诸如出血或肠穿孔等与淋巴瘤死亡率相关的并发症。
